Concept
Nerf optique
Publications associées (66)
Neuroprotection in the Retina: From Preventing Inflammatory Cell Death to Promoting Vascular Stability in the Central Nervous System
Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma is defined clinically as the presence of optic nerve head (ONH) degeneration and progressive loss of retinal ganglion cells (RGCs). Intra-ocular pressure (IOP) has been con ...
EPFL2024Modeling, fabrication and validation of 3D neural interfaces for peripheral nerves and brain organoids
This thesis presents an extensive exploration of neuroelectronic interfaces, focusing on microfabrication, in silico modeling, and their applications in designing and fabricating devices for neural interfacing. The research encompasses both peripheral nerv ...
EPFL2024Reconstruction of nerve functional topography using recruitment curves enables selective electrical stimulation
Silvestro Micera, Simone Romeni, Bianca Ziliotto
Multi-polar stimulation protocols have been used in the past to increase the selectivity of electrical stimulation of the nervous system. Nonetheless, the number of possible multipolar stimulation protocols is prohibitively large and cannot be explored dur ...
IEEE2023Recent Advances in Polymeric Drug Delivery Systems for Peripheral Nerve Regeneration
When a traumatic event causes complete denervation, muscle functional recovery is highly compromised. A possible solution to this issue is the implantation of a biodegradable polymeric tubular scaffold, providing a biomimetic environment to support the ner ...
MDPI2023Fabrication and validation of an intraneural interface tailored for optic nerve stimulation
Technological progress in materials science and microengineering along with new discoveries in neuroscience have contributed to restore lost or impaired sensory functions by closely interfacing with the nervous system. Electronic devices have begun to be i ...
EPFL2022Incomplete Recovery of Zebrafish Retina Following Cryoinjury
Zebrafish show an extraordinary potential for regeneration in several organs from fins to central nervous system. Most impressively, the outcome of an injury results in a near perfect regeneration and a full functional recovery. Indeed, among the various i ...
MDPI2022