Concept
Groupe de parole
Publications associées (6)
Trio preserves motor synapses and prolongs motor ability during aging
Evelyne Ruchti, Brian Donal McCabe, Soumya Banerjee, Greta Limoni, Samuel William Vernon, Wei Jiao
The decline of motor ability is a hallmark feature of aging and is accompanied by degeneration of motor synaptic terminals. Consistent with this, Drosophila motor synapses undergo characteristic age -dependent structural fragmentation co -incident with dim ...
Cell Press2024Identification of biopsychological trait markers in functional neurological disorders
Weber et al. provide evidence in support of a stress-diathesis model of functional neurological disorders. They identify trauma history in the form of emotional neglect as a psychological risk factor, and reduced hippocampus and amygdala volume as a predis ...
OXFORD UNIV PRESS2022Study of brain metabolic dysfunctions in animal models of mood disorder using magnetic resonance spectroscopy
Mood disorders, in particular depression, are a major burden of our society. Due to the poor knowledge of the biological basis of these diseases, classification remains based on arbitrary symptomatic parameters. As a result, the existing pharmacological tr ...
EPFL2020Deletion of CREB-Regulated Transcription Coactivator 1 Induces Pathological Aggression, Depression-Related Behaviors, and Neuroplasticity Genes Dysregulation in Mice
Jean-René Cardinaux, Christophe Mérinat
Background: Mood disorders are polygenic disorders in which the alteration of several susceptibility genes results in dysfunctional mood regulation. However, the molecular mechanisms underlying their transcriptional dysregulation are still unclear. The tra ...
Elsevier Science Inc2012