Concept

Effective population size

Publications associées (146)

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A workshop recently held at the École Polytechnique Fédérale de Lausanne (EPFL, Switzerland) was dedicated to understanding the genetic basis of adaptive change, taking stock of the different approaches developed in theoretical population genetics and land ...

Wiley-Blackwell2013

Population Synthesis: A Different Perspective

Michel Bierlaire, Bilal Farooq

Microsimulation of urban systems evolution requires synthetic population as a key input. Currently, the focus is on treating synthesis as a fitting problem and thus various techniques have been developed, including Iterative Proportional Fitting (IPF) and ...

2013

Simulation based Synthesis of Population

Michel Bierlaire, Gunnar Flötteröd, Bilal Farooq, Ricardo Daniel Hurtubia González

2013

Analysis of B. taurus and B. indicus admixture in Uganda as revealed by the Illumina BovineSNP50 Genotyping BeadChip

Stéphane Joost, Sylvie Stucki, Pierre Taberlet

The NextGen project investigates disease resistance in indigenous Ugandan cattle. Since population structure and stratification may produce biased results, We have investigated the genomic structure of sampled animals genotyped with the BovineSNP50 Genotyp ...

2013

Why to account for finite sites in population genetic studies and how to do this with Jaatha 2.0

With the advent of next-generation sequencing technologies, large data sets of several thousand loci from multiple conspecific individuals are available. Such data sets should make it possible to obtain accurate estimates of population genetic parameters, ...

Wiley-Blackwell2013

Simulations of driven overdamped frictionless hard spheres

Matthieu Wyart

Elsevier2013

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We present an array of micro artificial muscles developed for investigation of cells response to mechanical strain. Few technologies can be used to realise this type of study. However, in most cases a compromise is required and one must choose between high ...

2013

Biophysical controls on cluster dynamics and architectural differentiation of microbial biofilms in contrasting flow environments

Andrea Rinaldo, Tom Ian Battin, Enrico Bertuzzo, Lorenzo Mari, Samir Suweis

Ecology, with a traditional focus on plants and animals, seeks to understand the mechanisms underlying structure and dynamics of communities. In microbial ecology, the focus is changing from planktonic communities to attached biofilms that dominate microbi ...

Wiley-Blackwell2013

The niche under siege: novel targets for metastasis therapy

Albert Santamaria Martinez

Metastasis is an inefficient process and most cancer cells fail to colonize secondary sites. There are several possible reasons for this. First, the nature of the infiltrating cells is important as a small population of cancer stem cells has been shown to ...

Wiley-Blackwell2013

Alternative Restart Strategies for CMA-ES

Ilya Loshchilov

This paper focuses on the restart strategy of CMA-ES on multi-modal functions. A first alternative strategy proceeds by decreasing the initial step-size of the mutation while doubling the population size at each restart. A second strategy adaptively alloca ...

2012