Concept

Current Biology

Publications associées (13)

Developing new tools to study and program cell fate at the single-cell level

Single-cell transcriptomics (scRNA-seq) started a technological revolution in biology by enabling through the plethora of methods to assess a molecular state of the cell on systems level without the strict necessity of the prior knowledge of the cell state ...

EPFL2021

Empowering Global Chemical Biology at the Dawn of the New Decade

Yimon Aye

On January 22-24, 2020, scientific luminaries across the far-flung corners of chemical biology gathered in Geneva, Switzerland, to deliver their latest and greatest discoveries in the field. Generously supported by the Swiss National Science Foundation (SN ...

AMER CHEMICAL SOC2020

Chapter 16: Microbial Production of Flavonoids: Engineering Strategies for Improved Production

Edgard Gnansounou, Binod Parameswaran

Flavonoids are natural plant-derived compounds which have immense applications in pharmaceutical industry and have attracted the attention of both the industry and researchers involved in all fields of biology and medicine. Microbial production systems can ...

Wiley2019

Analysis of cellular and drug action mechanisms in the malaria parasites using systems biology approaches

Anush Chiappino-Pepe

Malaria puts at risk of infection half of the world population and still kills around half a million people every year. The rapid and worrisome rise of drug-resistant malaria parasites hinders the treatment of malaria and calls for a global collaboration t ...

EPFL2018

Microwave Imaging of Brain Stroke

Mina Bjelogrlic

Brain stroke is an age-related illness which has become a major issue in our ageing societies. Early diagnosis and treatment are of high importance for the full recovery of the patient, as reminded in Anglo-Saxon countries by the abbreviation FAST (Face, A ...

EPFL2018

Soil protistology rebooted: 30 fundamental questions to start with

Edward Mitchell, Vincent Eric Jules Jassey, Mariusz Lamentowicz, Enrique Lara, Thierry Jean Heger, Bertrand Fournier, Alexandre Jousset, Santosh Kumar

Protists are the most diverse eukaryotes. These microbes are keystone organisms of soil ecosystems and regulate essential processes of soil fertility such as nutrient cycling and plant growth. Despite this, protists have received little scientific attentio ...

Pergamon-Elsevier Science Ltd2017

Mathematical models and computational methods for the analysis of genome-scale protein synthesis

Julien Racle

Proteins are a ubiquitous and indispensable element for every living organism, from simple bacteria to mammals. Already in the simplest organisms, there exist some thousands of different protein species that take up a great variety of structures, and thus ...

EPFL2014

Progesterone signalling in breast cancer: a neglected hormone coming into the limelight

Cathrin Brisken

Abstract | Understanding the biology of the breast and how ovarian hormones impinge on it is key to rational new approaches in breast cancer prevention and therapy. Because of the success of selective oestrogen receptor modulators (SERMs), such as tamoxife ...

Nature Publishing Group2013

The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities

Michele De Palma, Douglas Hanahan

It is a time of great promise and expectation for the applications of knowledge about mechanisms of cancer toward more effective and enduring therapies for human disease. Conceptualizations such as the hallmarks of cancer are providing an organizing princi ...

2012

Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration

Matthias Lütolf, Philipp Sebastian Lienemann, Martin Ehrbar

The regeneration of large bone defects caused by trauma or disease remains a significant clinical problem. Although osteoinductive growth factors such as bone morphogenetic proteins have entered clinics, transplantation of autologous bone remains the gold ...

Elsevier Science Bv2012

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