Concept
Combined injectable birth control
Publications associées (40)
Bio-Enhanced Neoligaments Graft Bearing FE002 Primary Progenitor Tenocytes: Allogeneic Tissue Engineering & Surgical Proofs-of-Concept for Hand Ligament Regenerative Medicine
Corinne Scaletta, Sandra Jaccoud, Philippe Abdel Sayed, Nathalie Hirt-Burri, Cédric Peneveyre, Annick Jeannerat, Alexis Laurent, Joachim Meuli, Axelle Thomas
Hand tendon/ligament structural ruptures (tears, lacerations) often require surgical reconstruction and grafting, for the restauration of finger mechanical functions. Clinical-grade human primary progenitor tenocytes (FE002 cryopreserved progenitor cell so ...
MDPI2023Estrogen receptor signaling in the human breast epithelium
Breast cancer is the most diagnosed malignancy in women worldwide, making effective prevention strategies crucial. Hormonal contraceptives, consisting of a synthetic progesterone receptor agonist alone or in combination with an estrogen, are used by millio ...
EPFL2022Role of the androgen receptor in the human breast epithelium
Breast cancer is the most common malignancy in women worldwide and understanding the risk factors affecting it is key for prevention. The relative risk of developing breast cancer is related to exposure to both endogenous hormones and exogenous natural and ...
EPFL2022Two-step immobilization of metronidazole prodrug on TEMPO cellulose nanofibrils through thiol-yne click chemistry for in situ controlled release
David Lyndon Emsley, Jasmine Viger-Gravel, Michel Bardet, Julien Bras
Nowadays, drug encapsulation and drug release from cellulose nanofibrils systems are intense research topics, and commercial grades of cellulose nanomaterials are currently available. In this work we present an ester-containing prodrug of metronidazole tha ...
ELSEVIER SCI LTD2021Socioeconomic development predicts a weaker contraceptive effect of breastfeeding
The contraceptive effect of breastfeeding remains essential to controlling fertility in many developing regions of the world. The extent to which this negative effect of breastfeeding on ovarian activity is sensitive to ecological conditions, notably mater ...
NATL ACAD SCIENCES2021Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi-enzyme complexes in Escherichia coli
The peptidoglycan (PG) sacculus provides bacteria with the mechanical strength to maintain cell shape and resist osmotic stress. Enlargement of the mesh-like sacculus requires the combined activity of peptidoglycan synthases and hydrolases. In Escherichia ...
WILEY2020Mixture effects of drinking water disinfection by-products: implications for risk assessment
Disinfection by-products (DBPs) in drinking water have been associated with increased cancer risk but single DBPs cannot explain epidemiological cancer occurrences. To test if combined effects of DBPs are plausible to explain epidemiological evidence for a ...
ROYAL SOC CHEMISTRY2020Species-species interactions modulate copper toxicity under different visible light conditions
Combination of biotic and abiotic factors influences the effects of naturally occurring or anthropogenic chemicals on photosynthetic microorganisms in the aquatic environment. Nonetheless, the combined effects of physical stressors and species-species inte ...
ACADEMIC PRESS INC ELSEVIER SCIENCE2019Bio-optical properties and radiative energy budgets in fed and unfed scleractinian corals (Pocillopora sp.) during thermal bleaching
Niclas Heidelberg Lyndby, Michael Kühl
Corals live in symbiosis with algal dinoflagellates, which can achieve outstanding photosynthetic energy efficiencies in hospite approaching theoretical limits. However, how such photosynthetic efficiency varies with environmental stress remains poorly kno ...
2019Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions
Cathrin Brisken, Georgios Sflomos, Ayyakkannu Ayyanan, Laura Battista, Maryse Fiche, Valentina Scabia, Patrik Aouad, Valérian Charles Robert Dormoy
Estrogen receptor α-positive (ER-positive) or 'luminal' breast cancers were notoriously difficult to establish as patient-derived xenografts (PDXs). We and others recently demonstrated that the microenvironment is critical for ER-positive tumor cells; when ...
2018