Concept

Chitine

Publications associées (32)

The Regulatory Network of Natural Competence and Transformation of Vibrio cholerae

The human pathogen Vibrio cholerae is an aquatic bacterium frequently encountered in rivers, lakes, estuaries, and coastal regions. Within these environmental reservoirs, the bacterium is often found associated with zooplankton and more specifically with t ...

2012

Hydrophilic Nanogels

Catherine Ann Schütz

Hydrophilic nanocarriers, formed by electrostatic interaction between their oppositely charged components, are recognized as nanomaterials with an enormous potential as vectors in biomedical and pharmaceutical applications. However, comprehensive informati ...

EPFL2011

Development and Understanding of Novel Compounds Designed as Potential MRI Contrast Agents

Hugues Jaccard

The two last decades have witnessed the appearance and the successful development of magnetic resonance imaging (MRI) contrast agents (CAs). Though MRI, which has become an essential medical diagnostic tool, can be performed without contrast agents, its ra ...

EPFL2011

Cell Response to the Exposure to Chitosan-TPP//Alginate Nanogels

Jutta Christine Wandrey

Hydrophilic nanocarriers formed by electrostatic interaction of chitosan with oppositely charged macromolecules have a high potential as vectors in biomedical and pharmaceutical applications. However, comprehensive information about the fate of such nanoma ...

2011

Natural transformation of Vibrio cholerae as a tool - Optimizing the procedure

Melanie Blokesch

BACKGROUND: Vibrio cholerae gains natural competence upon growth on chitin. This allows the organism to take up free DNA from the environment and to incorporate it into its genome by homologous recombination. RESULTS: Making use of this developmental progr ...

BioMed Central2010

Chitosan-based nanogels for selective delivery of photosensitizers to macrophages and improved retention in and therapy of articular joints

Georges Wagnières, Jutta Christine Wandrey, Frédéric Schmitt, Jérôme Barge, Lucienne Lagopoulos

Macrophages play key roles in inflammatory disorders. Therefore, they are targets of treatments aiming at their local destruction in inflammation sites. However, injection of low molecular mass therapeutics, including photosensitizers, in inflamed joints r ...

Elsevier2010

Robotic laser tissue welding of sclera using chitosan films

Eric Tremblay, Pablo Garcia

Purpose: To demonstrate the feasibility of scleral wound closure using a novel adhesive made of chitosan film. Methods: Five-millimeter scleral lacerations were created in enucleated pig eyes. Casted chitosan films were sized to 7×7 mm patches. Lacerations ...

2009

The extracellular nuclease Dns and its role in natural transformation of Vibrio cholerae

Melanie Blokesch

Free extracellular DNA is abundant in many aquatic environments. While much of this DNA will be degraded by nucleases secreted by the surrounding microbial community, some is available as transforming material that can be taken up by naturally competent ba ...

American Society for Microbiology2008

Biocompatibility of bioresorbable poly(L-lactic acid) composite scaffolds obtained by supercritical gas foaming with human fetal bone cells

Dominique Pioletti, Pierre-Etienne Bourban, Boris Hinz

The aim of this investigation was to test the biocompatibility of three-dimensional bioresorbable foams made of poly(L-lactic acid) (PLA), alone or filled with hydroxyapatite (HA) or beta-tricalcium phosphate (beta-TCP), with human primary osteoblasts, usi ...

2005

Chitin induces natural competence in Vibrio cholerae

Melanie Blokesch, Karin Lederballe Meibom

The mosaic-structured Vibrio cholerae genome points to the importance of horizontal gene transfer (HGT) in the evolution of this human pathogen. We showed that V. cholerae can acquire new genetic material by natural transformation during growth on chitin, ...

American Association for the Advancement of Science2005

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