Concept

Hypoxie cérébrale

Publications associées (108)

EEG paradigms as a supplemental tool to behavioral assessments of DOC

José del Rocio Millán Ruiz, Andrea Serino, Serafeim Perdikis, Jean-Paul Noel

Introduction Diagnosis and prediction of recovery in the acute phase of disorders of consciousness (DOC) are critical for subsequent medical decisions. However, reliable assessment remains elusive due to the inability of current validated clinical scales t ...

2017

Randomized trial on the effects of a combined physical/cognitive training in aged MCI subjects: the Train the Brain study

Silvestro Micera, Giovanni D'Angelo, Martina Coscia, Marco Mainardi

Age-related cognitive impairment and dementia are an increasing societal burden. Epidemiological studies indicate that lifestyle factors, e.g. physical, cognitive and social activities, correlate with reduced dementia risk; moreover, positive effects on co ...

Nature Publishing Group2017

Study of cortical energy metabolism during sensory stimulation-induced brain activity by ¹³C magnetic resonance spectroscopy in vivo

Sarah Catherine Sonnay

Cerebral function is associated with high metabolic activity that is supported by continuous supply of oxygen and glucose from the blood. Coupling between brain energy metabolism and neuronal activity has been studied extensively during the past decades. N ...

EPFL2017

Dorsal and ventral stream contributions to form-from-motion perception in a patient with form-from motion deficit: a case report

Olaf Blanke, Manuel Mercier

The main model of visual processing in primates proposes an anatomo-functional distinction between the dorsal stream, specialized in spatio-temporal information, and the ventral stream, processing essentially form information. However, these two pathways a ...

2017

Lactoferrin during lactation reduces lipopolysaccharide-induced brain injury

Yohan Van de Looij

Lactoferrin (Lf), component of maternal milk, has antioxidant, anti-inflammatory and antimicrobial properties. Neuroprotective effects of Lf on the immature brain have been recently shown in rodent models of intrauterine growth restriction and cerebral hyp ...

Wiley-Blackwell2016

Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia

Yohan Van de Looij

Cerebral white matter injury is a leading cause of adverse neurodevelopmental outcome in prematurely born infants involving cognitive deficits in later life. Despite increasing knowledge about the pathophysiology of perinatal brain injury, therapeutic opti ...

Elsevier2016

Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury

Yohan Van de Looij

Cerebral white and grey matter injury is the leading cause of an adverse neurodevelopmental outcome in prematurely born infants. High oxygen concentrations have been shown to contribute to the pathogenesis of neonatal brain damage. Here, we focused on moto ...

Hindawi Limited2016

Effect of Hypoxia and Hyperoxia on Baroreflex Sensitivity

Jean-Marc Vesin, Sasan Yazdani

This paper is part of a series titled “AltitudeOmics” that together represent a group of studies that explore the basic mechanisms controlling human acclimatization to hypoxia. This study aims at analyzing the baroreflex sensitivity (BRS) at sea level, in ...

2016

Influence of Vascular Variant of the Posterior Cerebral Artery (PCA) on Cerebral Blood Flow, Vascular Response to CO2 and Static Functional Connectivity

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Daniela Maria Zöller, Kirsten Emmert

Introduction The fetal origin of the posterior cerebral artery (fPCA) is a frequent vascular variant in 11-29% of the population. For the fPCA, blood flow in the PCA originates from the anterior instead of the posterior circulation. We tested whether this ...

Public Library of Science2016

Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio

Pierre Magistretti, Reto Meuli, Luc Pellerin

Energy dysfunction is associated with worse prognosis after traumatic brain injury (TBI). Recent data suggest that hypertonic sodium lactate infusion (HL) improves energy metabolism after TBI. Here, we specifically examined whether the efficacy of HL (3h i ...

Mary Ann Liebert2016

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