Concept

Infertilité

Publications associées (28)

The Orphan Nuclear Receptor Nr5a2 Is Essential for Luteinization in the Female Mouse Ovary

In the ovary, the follicular granulosa cells express the nuclear receptor Nr5a2 (nuclear receptor subfamily 5 group A member 2), also known as liver receptor homolog-1, and after ovulation, Nr5a2 expression persists in the corpus luteum. Previous studies d ...

Endocrine Soc2014

VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy

Didier Trono, Jeffrey Alan Hubbell, Melody Swartz, Witold Waldemar Kilarski, Joseph Rutkowski, Seung Tae Lee, Miriella Carmela Pasquier, Jong Eun Ihm, Vivianne Greenwood

Lymphatic vessels surround follicles within the ovary, but their roles in folliculogenesis and pregnancy, as well as the necessity of Lymphangiogenesis in follicle maturation and health, are undefined. We used systemic delivery of mF4-31C1, a specific anta ...

Elsevier Science Inc2013

Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility

Alexandre Gattiker

Mammalian spermatogenesis is a process that involves a complex expression program in both somatic and germ cells present in the male gonad. A number of studies have attempted to define the transcriptome of male meiosis and gametogenesis in rodents and prim ...

Oxford University Press2012

Analysis of centriole elimination during C. elegans oogenesis

Pierre Gönczy, Graham Knott, Petr Strnad, Lukas von Tobel, Tamara Mikeladze-Dvali

Centrosomes are the principal microtubule organizing centers (MTOCs) of animal cells and comprise a pair of centrioles surrounded by pericentriolar material (PCM). Centriole number must be carefully regulated, notably to ensure bipolar spindle formation an ...

2012

Proangiogenic Tie2(+) macrophages infiltrate human and murine endometriotic lesions and dictate their growth in a mouse model of the disease

Michele De Palma, Daniela Biziato, Stefano Ferrari

Endometriosis affects women of reproductive age, causing infertility and pain. Although immune cells are recruited in endometriotic lesions, their role is unclear. Tie2-expressing macrophages (TEMs) have nonredundant functions in promoting angiogenesis and ...

2011

Pelvic Motion Implementation on the WalkTrainer

Reymond Clavel, Mohamed Bouri, Yves Stauffer, Patrick Métrailler, Jacques Fournier, Yves Allemand

Pelvic motion is of great importance when walking, and have thus to be taken into account while developing rehabilitation robotics. This paper describes the implementation of a pelvic motion amplitude prediction model on a pelvic orthosis and tests on vali ...

2007

A stochastic model of nitrate transport and cycling at basin scale

Andrea Rinaldo, Gianluca Botter

A stochastic framework for modelling catchment-scale hydrologic and nitrate responses (as a byproduct of transport processes and of a biogeochemical model of nitrogen cycling and transformations in heterogeneous soils) is proposed and applied to a 53 km2 b ...

2006

Modulators of ob gene and screening methods therefor

Johan Auwerx

This invention relates to the isolation and cloning of the promoter and other control regions of a human ob gene. It provides a method for identifying and screening for agents useful for the treatment of diseases and pathological conditions affected by the ...

1996

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