Publications associées à Population structure (genetics)

Seascape Genomics of the Sugar Kelp Saccharina latissima along the North Eastern Atlantic Latitudinal Gradient

Chloé Christiane Laurence Jollivet, Stéphane Mauger

Temperature is one of the most important range-limiting factors for many seaweeds. Driven by the recent climatic changes, rapid northward shifts of species' distribution ranges can potentially modify the phylogeographic signature of Last Glacial Maximum. W ...

MDPI2020

Limits on amplifiers of natural selection under death-Birth updating

Andreas Pavlogiannis

The fixation probability of a single mutant invading a population of residents is among the most widely-studied quantities in evolutionary dynamics. Amplifiers of natural selection are population structures that increase the fixation probability of advanta ...

PUBLIC LIBRARY SCIENCE2020

The population genetics of crypsis in vertebrates: recent insights from mice, hares, and lizards

Jeffrey David Jensen, Susanne Petra Pfeifer, Stefan Jean Laurent

By combining well-established population genetic theory with high-throughput sequencing data from natural populations, major strides have recently been made in understanding how, why, and when vertebrate populations evolve crypsis. Here, we focus on backgr ...

NATURE PUBLISHING GROUP2020

Sampling strategy optimization to increase statistical power in landscape genomics: a simulation-based approach

Stéphane Joost, Oliver Michele Selmoni, Estelle Rochat, Elia Vajana, Annie Sandrine Guillaume

An increasing number of studies are using landscape genomics to investigate local adaptation in wild and domestic populations. The implementation of this approach requires the sampling phase to consider the complexity of environmental settings and the burd ...

2020

Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion

Marion Leleu, Ludovica Vanzan, Flavia Marzetta, Ioannis Xenarios

Expanded CAG/CTG repeats underlie 13 neurological disorders, including myotonic dystrophy type 1 (DM1) and Huntington's disease (HD). Upon expansion, disease loci acquire heterochromatic characteristics, which may provoke changes to chromatin conformation ...

2020

Toward a Consensus View of Mammalian Adipocyte Stem and Progenitor Cell Heterogeneity

Bart Deplancke, Pernille Yde Rainer, Radiana Ferrero

White adipose tissue (WAT) is a cellularly heterogeneous endocrine organ that not only serves as an energy reservoir, but also actively participates in metabolic homeostasis. Among the main constituents of adipose tissue are adipocytes, which arise from ad ...

ELSEVIER SCIENCE LONDON2020

Predicting the Occurrence of Variants in RAG1 and RAG2

Jacques Fellay, Dylan Lawless, Flavia Aurelia Shoko Hodel

While widespread genome sequencing ushers in a new era of preventive medicine, the tools for predictive genomics are still lacking. Time and resource limitations mean that human diseases remain uncharacterized because of an inability to predict clinically ...

2019

Linking a mutation to survival in wild mice

Jeffrey David Jensen, Matthieu Foll, Susanne Petra Pfeifer, Stefan Jean Laurent

Adaptive evolution in new or changing environments can be difficult to predict because the functional connections between genotype, phenotype, and fitness are complex. Here, we make these explicit connections by combining field and laboratory experiments i ...

AMER ASSOC ADVANCEMENT SCIENCE2019

Mitochondrial haplotypes affect metabolic phenotypes in the Drosophila Genetic Reference Panel

Johan Auwerx, Bart Deplancke, Virginie Sandra Braman, Adamantia Kapopoulou, Maria Litovchenko, Brian Dennis Hollis, Roel Paulus Josephus Bevers

The nature and extent of mitochondrial DNA variation in a population and how it affects traits is poorly understood. Here we resequence the mitochondrial genomes of 169 Drosophila Genetic Reference Panel lines, identifying 231 variants that stratify along ...

2019

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Population structure (genetics)

Seascape Genomics of the Sugar Kelp Saccharina latissima along the North Eastern Atlantic Latitudinal Gradient

Limits on amplifiers of natural selection under death-Birth updating

The population genetics of crypsis in vertebrates: recent insights from mice, hares, and lizards

Sampling strategy optimization to increase statistical power in landscape genomics: a simulation-based approach

Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion

Toward a Consensus View of Mammalian Adipocyte Stem and Progenitor Cell Heterogeneity

Predicting the Occurrence of Variants in RAG1 and RAG2

Population structure determines the tradeoff between fixation probability and fixation time

Linking a mutation to survival in wild mice

Mitochondrial haplotypes affect metabolic phenotypes in the Drosophila Genetic Reference Panel

Graph Chatbot

Chattez avec Graph Search

Limits on amplifiers of natural selection under death-Birth updating

Seascape Genomics of the Sugar Kelp Saccharina latissima along the North Eastern Atlantic Latitudinal Gradient

The population genetics of crypsis in vertebrates: recent insights from mice, hares, and lizards

Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion

Predicting the Occurrence of Variants in RAG1 and RAG2

Sampling strategy optimization to increase statistical power in landscape genomics: a simulation-based approach

Linking a mutation to survival in wild mice

Toward a Consensus View of Mammalian Adipocyte Stem and Progenitor Cell Heterogeneity

Population structure determines the tradeoff between fixation probability and fixation time

Mitochondrial haplotypes affect metabolic phenotypes in the Drosophila Genetic Reference Panel