Concept

Éminence ganglionnaire

Publications associées (53)

Interneurons of the neocortical inhibitory system

Henry Markram, Gilad Silberberg, Yi Wang

Mammals adapt to a rapidly changing world because of the sophisticated cognitive functions that are supported by the neocortex. The neocortex, which forms almost 80% of the human brain, seems to have arisen from repeated duplication of a stereotypical micr ...

2004

Perinatal and early postnatal changes in the expression of monocarboxylate transporters MCT1 and MCT2 in the rat forebrain

Pierre Magistretti, Maxime Olivier Baud, Luc Pellerin

In addition to glucose, monocarboxylates including lactate represent a major source of energy for the brain, especially during development. We studied the immunocytochemical expression of the monocarboxylate transporters MCT1 and MCT2 in the rat brain betw ...

2003

Neuroprotective effect of interleukin-6 and IL6/IL6R chimera in the quinolinic acid rat model of Huntington's syndrome

Patrick Aebischer, Jean-Charles Bensadoun

Ciliary neurotrophic factor prevents behavioural deficits and striatal degeneration in rat and primate models of Huntington's disease. Interleukin- 6, another member of the cytokine family, and the chimeric molecule (IL6/IL6R) in which interleukin-6 and it ...

2001

Organizing principles for a diversity of GABAergic interneurons and synapses in the neocortex

Henry Markram, Yi Wang

A puzzling feature of the neocortex is the rich array of inhibitory interneurons. Multiple neuron recordings revealed numerous electrophysiological-anatomical subclasses of neocortical gamma-aminobutyric acid-ergic (GABAergic) interneurons and three types ...

2000

Opposite regulation of calbindin and calretinin expression by brain-derived neurotrophic factor in cortical neurons

Pierre Magistretti, Jean-Luc Martin

Regulation of calbindin and calretinin expression by brain-derived neurotrophic factor (BDNF) was examined in primary cultures of cortical neurons using immunocytochemistry and northern blot analysis. Here we report that regulation of calretinin expression ...

2000

OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos

Pierre Gönczy

Asymmetric cell divisions require the establishment of an axis of polarity, which is subsequently communicated to downstream events. During the asymmetric cell division of the P(1) blastomere in C. elegans, establishment of polarity depends on the establis ...

2000

Synchrotron spectromicroscopy of cobalt accumulation in granule cells, glial cells and GABAergic neurons

Giorgio Margaritondo

Recent neurobiophysics experiments based on synchrotron spectromicroscopy indicated that aluminium is selectively accumulated by GABAergic neurons and glial cells rather than by granule cells. Does a similar cell specificity occur in the accumulation of ot ...

1996

Cortical domains and the mechanisms of asymmetric cell division

Pierre Gönczy

Asymmetric cell divisions are central to the generation of cell-fate diversity because factors that are present in a mother cell and distributed unequally at cell division can generate distinct daughters. The process o f asymmetric cell division can be des ...

1996

Adenosine triphosphate and arachidonic acid stimulate glycogenolysis in primary cultures of mouse cerebral cortical astrocytes

Pierre Magistretti, Luc Pellerin

Adenosine triphosphate (ATP) promotes glycogenolysis in primary cultures of mouse cerebral cortical astrocytes with an EC50 of 1.5 microM. A pharmacological analysis indicates an involvement of purinergic P2Y receptors in this action of ATP. Application of ...

1995

Aluminum in Rat Cerebellar Primary Cultures - Glial-Cells and Gabaergic Neurons

Giorgio Margaritondo

EXPERIMENTAL evidence of the preferential uptake of aluminium by GABAergic neurones and glial cells was provided by synchrotron spectromicroscopy studies. We observed rat cerebellar cultures enriched for GABAergic neurones or glial cells exposed to alumini ...

1994

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