Concept
Lymphœdème
Publications associées (53)
Hydro-Mechanical Characterization of a Shale by Unusually High-Pressure Oedometric Tests
Alessio Ferrari, Eleonora Crisci
The note presents selected results of an experimental campaign conducted with the aim to investigate the hydro-mechanical behaviour of a shale recovered at a depth of about 900 m below the ground. High-pressure oedometric tests were performed to investigat ...
Wei Wu, Universität für Bodenkultur2023FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure
Mauro Delorenzi, Alexis Rapin, Dominique Velin, Esther Bovay, François Renevey
The mechanisms maintaining adult lymphatic vascular specialization throughout life and their role in coordinating inter-organ communication to sustain homeostasis remain elusive. We report that inactivation of the mechanosensitive transcription factor Foxc ...
AMER ASSOC ADVANCEMENT SCIENCE2021Experimental Drainage Device to Reduce Lymphoedema in a Rat Model
Nikolaos Stergiopoulos, Marco Pisano, Valentina Triacca, Melody Swartz
Objective: Despite recent advances in pharmacological research and microsurgery, lymphoedema remains an incurable disease that deeply affects quality of life. There is an urgent need for innovative approaches to restore continuous lymph flow in affected ti ...
W B SAUNDERS CO LTD2019Inherent biomechanical traits enable infective filariae to disseminate through collecting lymphatic vessels
Marco Pisano, Melody Swartz, Witold Waldemar Kilarski
Filariases are diseases caused by arthropod-borne filaria nematodes. The related pathologies depend on the location of the infective larvae when their migration, the asymptomatic and least studied phase of the disease, comes to an end. To determine factors ...
Springer2019Lymphatic vessel density is associated with CD8(+) T cell infiltration and immunosuppressive factors in human melanoma
Melody Swartz, Manuel Andreas Fankhauser, Natacha Anne-Sophie Bordry, Maria Anna Sofia Broggi, Esther Danenberg, Timothy Murray, Olivier Michielin
Increased density of tumor-associated lymphatic vessels correlates with poor patient survival in melanoma and other cancers, yet lymphatic drainage is essential for initiating an immune response. Here we asked whether and how lymphatic vessel density (LVD) ...
TAYLOR & FRANCIS INC2018Multiple roles of lymphatic vessels in peripheral lymph node development
Borja Prat Luri, Esther Bovay, Ann-Helen Willrodt
The mammalian lymphatic system consists of strategically located lymph nodes (LNs) embedded into a lymphatic vascular network. Mechanisms underlying development of this highly organized system are not fully understood. Using highresolution imaging, we show ...
2018Elucidating the role of lymphatic vessels within the tumor microenvironment of breast cancer
Breast cancer is the most common cancer in women worldwide, with an estimated 1.7 million newly diagnosed cases in 2012. Despite the many clinical manifestations, metastatic disease is the main cause of death, and is responsible for 90% of all breast cance ...
EPFL2017Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
Nicola Harris, Lalit Kumar Dubey, Praneeth Karempudi
Lymphatic growth (lymphangiogenesis) within lymph nodes functions to promote dendritic cell entry and effector lymphocyte egress in response to infection or inflammation. Here we demonstrate a crucial role for lymphotoxin-beta receptor (LT beta R) signalin ...
Springer Nature2017Exploiting lymphatic vessels for immunomodulation: Rationale, opportunities, and challenges
Melody Swartz, Lambert Charles François Potin
Lymphatic vessels are the primary route of communication from peripheral tissues to the immune system; as such, they represent an important component of local immunity. In addition to their transport functions, new immunomodulatory roles for lymphatic vess ...
Elsevier Science Bv2017Medical fluid drainage system
Marco Pisano, Valentina Triacca
A medical fluid drainage system which may be advantageously used to actively absorb excess fluid from an interstitium in a living host and to transport it from an inlet member 1 in a non edematous body part out of an outlet member 4 via pumps (5, 6, 7) bui ...
2016