Concept
Sac amniotique
Publications associées (25)
In vitro endoderm emergence and self-organisation in the absence of extraembryonic tissues and embryonic architecture
In humans, mice, and other mammals key internal organs such as the gut, the lungs, the pancreas, and the liver all derive from the same embryonic tissue: the endoderm. The development of all of these structures thus depends on a same set of early cells, an ...
EPFL2022Fighting preterm birth with novel surgical tools and biomaterials engineering
With advances in fetal diagnosis and therapy, fetoscopy has become a good option to treat a series of life threatening diseases like twin-to-twin transfusion syndrome or severe congenital diaphragmatic hernia. The efficacy of fetoscopy for those types of d ...
EPFL2017Tissue engineering for prenatal applications
Fetal therapies have become available for a restricted number of life-threatening clinical conditions. Harnessing tissue engineering for prenatal applications has not been widely pursued even though isolating cells from fetal and extraembryonic tissues has ...
EPFL2015Anthrax toxin receptor 2a controls mitotic spindle positioning
Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami
Oriented mitosis is essential during tissue morphogenesis. The Wnt/planar cell polarity (Wnt/PCP) pathway orients mitosis in a number of developmental systems, including dorsal epiblast cell divisions along the animal-vegetal (A-V) axis during zebrafish ga ...
Nature Publishing Group2013Embryonic stem cell potency fluctuates with endogenous retrovirus activity
Embryonic stem (ES) cells are derived from blastocyst-stage embryos and are thought to be functionally equivalent to the inner cell mass, which lacks the ability to produce all extraembryonic tissues. Here we identify a rare transient cell population withi ...
2012Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep
Yohan Van de Looij, François Lazeyras
Preterm infants exhibit chronic deficits in white matter (WM) and cortical maturation. Although fetal infection/inflammation may contribute to WM pathology, the factors contributing to cortical changes are largely unknown. We examined the effect of fetal l ...
2011