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Publications associées (34)
Genomic Diversity of Torque Teno Virus in Blood Samples from Febrile Paediatric Outpatients in Tanzania: A Descriptive Cohort Study
Torque teno virus (TTV) is considered to be an ubiquitous member of the commensal human blood virome commonly reported in mixed genotype co-infections. This study investigates the genomic diversity of TTV in blood samples from 816 febrile Tanzanian childre ...
MDPI2022Transient vitamin B5 starving improves mammalian cell homeostasis and protein production
Maintaining a metabolic steady state is essential for an organism's fitness and survival when confronted with environmental stress, and metabolic imbalance can be reversed by exposing the organism to fasting. Here, we attempted to apply this physiological ...
ACADEMIC PRESS INC ELSEVIER SCIENCE2020Contribution of Genetic Background and Data Collection on Adverse Events of Anti-human Immunodeficiency Virus (HIV) Drugs (D:A:D) Clinical Risk Score to Chronic Kidney Disease in Swiss HIV-infected Persons With Normal Baseline Estimated Glomerular Filtration Rate
Jacques Fellay, Christian Axel Wandall Thorball
Background. In human immunodeficiency virus (HIV), the relative contribution of genetic background, clinical risk factors, and antiretrovirals to chronic kidney disease (CKD) is unknown. Methods. We applied a case-control design and performed genome-wide g ...
OXFORD UNIV PRESS INC2020Time-dependent mediators in survival analysis: Modeling direct and indirect effects with the additive hazards model
We discuss causal mediation analyses for survival data and propose a new approach based on the additive hazards model. The emphasis is on a dynamic point of view, that is, understanding how the direct and indirect effects develop over time. Hence, importan ...
2020Spatial Areas of Genotype Probability (SPAG): predicting the spatial distribution of adaptive genetic variants under future climatic conditions
Stéphane Joost, Estelle Rochat
In a context of rapid global change, one of the key components for the survival of species is their genetic adaptive potential. Many methods have been developed to identify adaptive genetic variants, but few tools were made available to integrate this know ...
2019The fitness landscape of the codon space across environments
Jeffrey David Jensen, Claudia Bank, Sebastian Matuszewski
Fitness landscapes map the relationship between genotypes and fitness. However, most fitness landscape studies ignore the genetic architecture imposed by the codon table and thereby neglect the potential role of synonymous mutations. To quantify the fitnes ...
NATURE PUBLISHING GROUP2018Sexual selection shapes development and maturation rates in Drosophila
Laurent Keller, Brian Dennis Hollis
Explanations for the evolution of delayed maturity usually invoke trade-offs mediated by growth, but processes of reproductive maturation continue long after growth has ceased. Here, we tested whether sexual selection shapes the rate of posteclosion matura ...
Wiley2017