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Chimeric antigen receptor (CAR) T cells in the solid tumor microenvironment enter a partially dysfunctional state called T cell exhaustion. Interleukin (IL)-10-producing CAR T cells retain their metabolic fitness, resist T cell exhaustion and display unpre ...
Berlin2024
Sedentary lifestyle is currently considered a global pandemic, associated with major health problems such as cardiovascular disease and premature death. Regular physical activity (PA) is one way to address this problem, as it brings a variety of health ben ...
EPFL2023
Background: The relationship between amino acids, B vitamins, and their metabolites with D3-creatine (D3Cr) dilution muscle mass, a more direct measure of skeletal muscle mass, has not been investigated. We aimed to assess associations of plasma metabolite ...
Cary2023
New approaches are needed to address low physical activity levels among older adults and to promote daily physical activity tailored to their interests and abilities. This study aimed to review the current literature analyzing the physiological demands of ...
HUMAN KINETICS PUBL INC2023
Human motion analysis and synthesis is integral to many computer vision applications, from autonomous driving to sports analysis. In this thesis, we address several problems in this domain. First we consider active viewpoint selection for pose estimation w ...
This paper numerically evaluates the accuracy and performance of a stabilized finite element Reduced Order Modelling (ROM) approach that is designed to simulate pulsatile blood flows. The method is able to estimate fluid flow parametric solutions of intere ...
Sweat secreted by the human eccrine sweat glands can provide valuable biomarker information during exercise. Real-time non-invasive biomarker recordings are therefore useful for evaluating the physiological conditions of an athlete such as their hydration ...
This collection of essays, all authored and curated by Tim Waterman, foregrounds the entangled nature of utopia(nism), landscape (aka landship), design and imagination, where ‘everything is connected, everything is inseparable, everything can have differen ...
The age-related loss of skeletal muscle function starts from midlife and if left unaddressed can lead to an impaired quality of life. A growing body of evidence indicates that mitochondrial dysfunction is causally involved with muscle aging. Muscles are ti ...
Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...
