Concept

Cancer de la vessie

Publications associées (109)

Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Blaise Lovisa, Carla Martoccia

Fluorescence cystoscopy enhances detection of early bladder cancer. Water used to inflate the bladder during the procedure rapidly contains urine, which may contain fluorochromes. This frequently degrades fluorescence images. Samples of bladder washout flu ...

Spie-Soc Photo-Optical Instrumentation Engineers2014

GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer

Bart Deplancke, Natasha Ella Samson, Etienne Meylan, Petra Catalina Schwalie, Svenja Johanna Groeneveld, Jessica Christine Vazquez, Mark Jonathan Masin

Alterations in glucose metabolism and epithelial-mesenchymal transition (EMT) constitute two important characteristics of carcinoma progression toward invasive cancer. Despite an extensive characterization of each of them separately, the links between EMT ...

2014

Development of a Database for Translational Spinal Cord Injury Research

Grégoire Courtine

Efforts to understand spinal cord injury (SCI) and other complex neurotrauma disorders at the pre-clinical level have shown progress in recent years. However, successful translation of basic research into clinical practice has been slow, partly because of ...

Mary Ann Liebert2014

Tumor Vessel Normalization by Chloroquine Independent of Autophagy

Freddy Radtke

Chloroquine (CQ) has been evaluated as an autophagy blocker for cancer treatment, but it is unknown if it acts solely by inhibiting cancer cell autophagy. We report that CQ reduced tumor growth but improved the tumor milieu. By normalizing tumor vessel str ...

Elsevier2014

Clonal, Self-Renewing and Differentiating Human and Porcine Urothelial Cells, a Novel Stem Cell Population

Yann Barrandon, Peter Frey, Jeffrey Alan Hubbell, Hans Mattias Larsson, François Gorostidi

Although urothelial progenitor-like cells have been described in the human urinary tract, the existence of stem cells remains to be proven. Using a culture system that favors clonogenic epithelial cell growth, we evaluated and characterized clonal human ur ...

Public Library of Science2014

Low-dose angiostatic tyrosine kinase inhibitors improve photodynamic therapy for cancer: lack of vascular normalization

Paul Joseph Dyson, Patrycja Nowak-Sliwinska, Débora Bonvin

Photodynamic therapy (PDT) is an effective clinical treatment for a number of different cancers. PDT can induce hypoxia and inflammation, pro-angiogenic side effects, which may counteract its angio-occlusive mechanism. The combination of PDT with anti-angi ...

2014

Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer

Anguraj Sadanandam, Shan Jiang

Activating mutations in KRAS are among the most frequent events in diverse human carcinomas and are particularly prominent in human pancreatic ductal adenocarcinoma (PDAC). An inducible Kras(G12D) driven mouse model of PDAC has established a critical role ...

Cell Press2014

A Microchannel Neuroprosthesis for Bladder Control After Spinal Cord Injury in Rat

Stéphanie Lacour, Ivan Rusev Minev, Katherine Marie Musick

A severe complication of spinal cord injury is loss of bladder function (neurogenic bladder), which is characterized by loss of bladder sensation and voluntary control of micturition (urination), and spontaneous hyperreflexive voiding against a closed sphi ...

American Association for the Advancement of Science2013

Multisystem Neuroprosthetic Training Improves Bladder Function After Severe Spinal Cord Injury

Grégoire Courtine, Rubia van den Brand, Daniel Eberli

Severe spinal cord injury leads to neurogenic bladder dysfunction. We recently developed a multisystem neuroprosthetic training program that promotes plastic changes capable of restoring refined locomotion in rats with severe spinal cord injury. We investi ...

Elsevier Science Inc2013

Metastasis: New insights into organ-specific extravasation and metastatic niches

Anja Irmisch

The appearance of clinically detectable metastases is the end-point of a complex set of biological processes only few cancer cells are capable to complete. Metastatic colonization comprises the most inefficient metastatic steps as it requires a fine-tuned ...

Elsevier2013

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