Concept

Flavine mononucléotide

Publications associées (15)

Redox Properties of Flavin in BLUF and LOV Photoreceptor Proteins from Hybrid QM/MM Molecular Dynamics Simulation

Flavins play an important role in many oxidation and reduction processes in biological systems. For example, flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) are common cofactors found in enzymatic proteins that use the special redox prope ...

Amer Chemical Soc2024

Implementation of a flavin biosynthesis operon improves extracellular electron transfer in bioengineered Escherichia coli

Ardemis Anoush Boghossian, Melania Reggente, Mohammed Mouhib

Bioelectrochemical systems (BES) are promising for energy, sensing, environmental, and synthesis applications. Escherichia coli were previously bioengineered for application in BES by introduction of extracellular electron transfer (EET) pathways. Inspired ...

2023

Two-step immobilization of metronidazole prodrug on TEMPO cellulose nanofibrils through thiol-yne click chemistry for in situ controlled release

David Lyndon Emsley, Jasmine Viger-Gravel, Michel Bardet, Julien Bras

Nowadays, drug encapsulation and drug release from cellulose nanofibrils systems are intense research topics, and commercial grades of cellulose nanomaterials are currently available. In this work we present an ester-containing prodrug of metronidazole tha ...

ELSEVIER SCI LTD2021

RdhC, a family of membrane-bound flavoproteins involved in electron transfer in organohalide respiration ?

Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Géraldine Florence Buttet

Organohalide respiration (OHR) is a bacterial energy metabolism making use of halogenated compounds – like tetrachloroethene (PCE), a major pollutant – as terminal electron acceptors. Three models of electron transport chain exist for OHR [1], however many ...

2018

The membrane-bound C subunit of reductive dehalogenases: topology analysis and reconstitution of the FMN-binding domain of PceC

Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Géraldine Florence Buttet, Aamani Rupakula Boyanapalli

Organohalide respiration (OHR) is the energy metabolism of anaerobic bacteria able to use halogenated organic compounds as terminal electron acceptors. While the terminal enzymes in OHR, so-called reductive dehalogenases, are well-characterized, the identi ...

Frontiers Media SA2018

The Membrane-Bound C Subunit of Reductive Dehalogenases: Topology Analysis and Reconstitution of the FMN-Binding Domain of PceC

Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Géraldine Florence Buttet, Aamani Rupakula Boyanapalli

2018

Development of new strategies to produce and characterize PceC, a membrane-bound flavoprotein involved in organohalide respiration

Christof Holliger, Lorenzo Cimmino

Halogenated organic compounds (so-called organohalides) represent one of the major widespread groundwater pollutants. Organohalide respiration (OHR) is a bacterial anaerobic process in which chlorinated compound, e.g. tetrachloroethene (PCE), is used as te ...

2018

Non-invasive continuous monitoring of pro-oxidant effects of engineered nanoparticles on aquatic microorganisms

Olivier Martin, Paul Bowen, Christian Santschi, Volodymyr Koman, Nadia Rachel Von Moos

Engineered nanomaterials (ENMs) are key drivers for the development of highly sophisticated new technologies. As all new attainments, the rapidly increasing used of ENMs raise concerns about their safety for the environment and humans. There is growing evi ...

2017

Electric-Field-Driven Direct Desulfurization

Klaus Kern, Hagen Klauk, Uta Schlickum, Peter Wahl, Ivan Pentegov, Verena Katharina Schendel

The ability to elucidate the elementary steps of a chemical reaction at the atomic scale is important for the detailed understanding of the processes involved, which is key to uncover avenues for improved reaction paths. Here, we track the chemical pathway ...

Amer Chemical Soc2017

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser

Detection of cytoplasmic DNA represents one of the most fundamental mechanisms of the innate immune system to sense the presence of microbial pathogens. Moreover, erroneous detection of endogenous DNA by the same sensing mechanisms has an important pathoph ...

2013

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