Publications associées à Anémie aplasique

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in LdIr(-/-) Mice

Non-alcoholic steatohepatitis (NASH) is characterized by liver steatosis and inflammation. Currently, the underlying mechanisms leading to hepatic inflammation are not fully understood and consequently, therapeutic options are poor. Non-alcoholic steatohep ...

Public Library of Science2016

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

Cyrille Dunant

In a classical view of hematopoiesis, the various blood cell lineages arise via a hierarchical scheme starting with multipotent stem cells that become increasingly restricted in their differentiation potential through oligopotent and then unipotent progeni ...

Amer Assoc Advancement Science2016

Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis

Olaia Maria Naveiras Torres-Quiroga, Nan Li

Blood flow promotes emergence of definitive hematopoietic stem cells (HSCs) in the developing embryo, yet the signals generated by hemodynamic forces that influence hematopoietic potential remain poorly defined. Here we show that fluid shear stress endows ...

2015

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fc gamma Receptor I

Arne Seitz, Romain Guiet, Duncan-Bruce Sutherland, Nicola Harris, Benjamin John Marsland, Beatrice Volpe, Julia Esser-von Bieren, Manuel Kulagin

Infections with intestinal helminths severely impact on human and veterinary health, particularly through the damage that these large parasites inflict when migrating through host tissues. Host immunity often targets the motility of tissue-migrating helmin ...

Amer Assoc Immunologists2015

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

Eva Sabrina Gollwitzer, Nicola Harris, Benjamin John Marsland

Metabolites from intestinal microbiota are key determinants of host-microbe mutualism and, consequently, the health or disease of the intestinal tract. However, whether such host-microbe crosstalk influences inflammation in peripheral tissues, such as the ...

Nature Publishing Group2014

Cell-wall deficient L. monocytogenes L-forms feature abrogated pathogenicity

Nicola Harris

Stable L-forms are cell wall-deficient bacteria which are able to multiply and propagate indefinitely, despite the absence of a rigid peptidoglycan cell wall. We investigated whether L-forms of the intracellular pathogen L. monocytogenes possibly retain pa ...

Frontiers Research Foundation2014

Conditional Deletion of Ferritin H in Mice Reduces B and T Lymphocyte Populations

Liviu Vanoaica, Maike Jaworski

The immune system and iron availability are intimately linked as appropriate iron supply is needed for cell proliferation, while excess iron, as observed in hemochromatosis, may reduce subsets of lymphocytes. We have tested the effects of a ferritin H gene ...

Public Library of Science2014

Discovery of a Highly Tumor-Selective Organometallic Ruthenium(II)-Arene Complex

Paul Joseph Dyson, Rosario Scopelliti, Patrycja Nowak-Sliwinska, Catherine Marie Amélie Clavel, Emilia Paunescu

A ruthenium(II)-arene complex with a perfluoroalkyl-ligand was found to display remarkable selectivity toward cancer cells. IC50 values on several cancer cell lines are in the range of 25-45 mu M, and no cytotoxic effect was observed on nontumorigenic (HEK ...

Amer Chemical Soc2014

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Anémie aplasique

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in LdIr(-/-) Mice

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis

Accumulation of amino-polyvinyl alcohol-coated superparamagnetic iron oxide nanoparticles in bone marrow: implications for local stromal cells

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fc gamma Receptor I

PPAR beta/delta activation of CD300a controls intestinal immunity

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

Cell-wall deficient L. monocytogenes L-forms feature abrogated pathogenicity

Conditional Deletion of Ferritin H in Mice Reduces B and T Lymphocyte Populations

Discovery of a Highly Tumor-Selective Organometallic Ruthenium(II)-Arene Complex

Graph Chatbot

Chattez avec Graph Search

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fc gamma Receptor I

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in LdIr(-/-) Mice

Cell-wall deficient L. monocytogenes L-forms feature abrogated pathogenicity

PPAR beta/delta activation of CD300a controls intestinal immunity

Discovery of a Highly Tumor-Selective Organometallic Ruthenium(II)-Arene Complex

Accumulation of amino-polyvinyl alcohol-coated superparamagnetic iron oxide nanoparticles in bone marrow: implications for local stromal cells

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

Conditional Deletion of Ferritin H in Mice Reduces B and T Lymphocyte Populations