Concept
Longévité
Publications associées (34)
Towards learning-based image compression for storage on DNA support
Touradj Ebrahimi, Michela Testolina
The demand for data storage has grown exponentially over the past decades. Current archival solutions have significant shortcomings, such as high resource requirements and a lack of sufficient longevity. In contrast, research on DNA-based storage has been ...
2023Is There a Cap on Longevity? A Statistical Review
There is sustained and widespread interest in understanding the limit, if there is any, to the human life span. Apart from its intrinsic and biological interest, changes in survival in old age have implications for the sustainability of social security sys ...
ANNUAL REVIEWS2022Human mortality at extreme age
We use a combination of extreme value statistics, survival analysis and computer-intensive methods to analyse the mortality of Italian and French semi-supercentenarians. After accounting for the effects of the sampling frame, extreme-value modelling leads ...
ROYAL SOC2021Demography of galactic technosignatures
Probabilistic arguments about the existence of technological life beyond Earth traditionally refer to the Drake equation to draw possible estimates of the number of technologically advanced civilizations releasing, either intentionally or not, electromagne ...
OXFORD UNIV PRESS2021Gene-by-environment modulation of lifespan and weight gain in the murine BXD family
Johan Auwerx, Maroun Bou Sleiman, Evan Graehl Williams, Pooja Jha
How lifespan and body weight vary as a function of diet and genetic differences is not well understood. Here we quantify the impact of differences in diet on lifespan in a genetically diverse family of female mice, split into matched isogenic cohorts fed a ...
NATURE PORTFOLIO2021NAD(+) homeostasis in health and disease
Johan Auwerx, Mario Romani, Elena Katsyuba, Dina Hofer
The conceptual evolution of nicotinamide adenine dinucleotide (NAD(+)) from being seen as a simple metabolic cofactor to a pivotal cosubstrate for proteins regulating metabolism and longevity, including the sirtuin family of protein deacylases, has led to ...
NATURE PUBLISHING GROUP2020