Publications associées à Natalizumab

Accurate Diagnosis of Cortical and Infratentorial Lesions in Multiple Sclerosis Using Accelerated Fluid and White Matter Suppression Imaging

Objectives: The precise location of multiple sclerosis (MS) cortical lesions can be very challenging at 3 T, yet distinguishing them from subcortical lesions is essential for the diagnosis and prognosis of the disease. Compressed sensing-accelerated fluid ...

LIPPINCOTT WILLIAMS & WILKINS2023

Serum GFAP in multiple sclerosis: correlation with disease type and MRI markers of disease severity

Tobias Kober, Bénédicte Marie Maréchal, Mario Joao Fartaria de Oliveira, Ricardo Alberto Corredor Jerez

Neurofilament light chain (NfL) has been demonstrated to correlate with multiple sclerosis disease severity as well as treatment response. Nevertheless, additional serum biomarkers are still needed to better differentiate disease activity from disease prog ...

Nature Research2020

An Ultra-High Field Study of Cerebellar Pathology in Early Relapsing-Remitting Multiple Sclerosis Using MP2RAGE

Meritxell Bach Cuadra, Tobias Kober, Gunnar Krüger, Cristina Granziera, Alexis Roche, Kieran O'Brien, Guillaume Bonnier, Mario Joao Fartaria de Oliveira, Pavel Falkovskiy

Objectives: The aim of this study was to study focal cerebellar pathology in early stages of multiple sclerosis (MS) using ultra-high-field magnetization-prepared 2 inversion-contrast rapid gradient-echo (7T MP2RAGE). Materials and Methods: Twenty early-st ...

Lippincott, Williams & Wilkins2017

Multicontrast connectometry: A new tool to assess cerebellum alterations in early relapsing‐remitting multiple sclerosis

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, David Paul Roger Romascano, Alessandro Daducci, Cristina Granziera, Djalel Eddine Meskaldji, Jonas Richiardi, Gunnar Krüger, Alexis Roche, Guillaume Bonnier

Background: Cerebellar pathology occurs in late multiple sclerosis (MS) but little is known about cerebellar changes during early disease stages. In this study, we propose a new multicontrast “connectometry” approach to assess the structural and functional ...

Wiley-Blackwell2015

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis

Jean-Philippe Thiran, David Paul Roger Romascano, Djalel Eddine Meskaldji, Cristina Granziera, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

In patients with multiple sclerosis (MS), conventional magnetic resonance imaging (MRI) provides only limited insights into the nature of brain damage with modest clinic-radiological correlation. In this study, we applied recent advances in MRI techniques ...

2014