Publications associées à Crête neurale

A Subpopulation of Smooth Muscle Cells, Derived from Melanocyte-Competent Precursors, Prevents Patent Ductus Arteriosus

Background: Patent ductus arteriosus is a life-threatening condition frequent in premature newborns but also present in some term infants. Current mouse models of this malformation generally lead to perinatal death, not reproducing the full phenotypic spec ...

Public Library of Science2013

Cooperative Roles of SDF-1 alpha and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

Melody Swartz, Mingming Wu

Chemokine-mediated directed tumor cell migration within a three dimensional (3D) matrix, or chemoinvasion, is an important early step in cancer metastasis. Despite its clinical importance, it is largely unknown how cytokine and growth factor gradients with ...

Public Library of Science2013

Maria del Carmen Sandi Perez, Reto Bisaz, David Genoux

Most of the mechanisms involved in neural plasticity support cognition, and aging has a considerable effect on some of these processes. The neural cell adhesion molecule (NCAM) of the immunoglobulin superfamily plays a pivotal role in structural and functi ...

Cold Spring Harbor Lab Press, Publications Dept2013

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

David Michael Suter, Mathurin Baquié

Neural differentiation of embryonic stem cells (ESC) is considered a promising model to perform in vitro testing for neuroactive and neurotoxic compounds. We studied the potential of a dual reporter murine ESC line to identify bioactive and/or toxic compou ...

2013

Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS

Philippe Renaud, Pierre Magistretti, Patrick Aebischer, Sylvain Eric Lengacher, Anja Kunze, Elisabeth Anne Dirren

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. ALS is believed to be a non-cell autonomous condition, as other cell types, including astrocytes, have been implicated in disease pathogenesis. Hence, to facilitate the developmen ...

Royal Soc Chemistry2013

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

Matthias Lütolf, Marlen Knobloch

Mechanisms controlling the proliferative activity of neural stem and progenitor cells (NSPCs) have a pivotal role to ensure life-long neurogenesis in the mammalian brain(1). How metabolic programs are coupled with NSPC activity remains unknown. Here we sho ...

Nature Publishing Group2013

A Computational Model for Epidural Electrical Stimulation of Spinal Sensorimotor Circuits

Silvestro Micera, Grégoire Courtine, Marco Capogrosso, Stanisa Raspopovic, Pavel Musienko, Nikolaus Wenger, Janine Beauparlant

Epidural electrical stimulation (EES) of lumbosacral segments can restore a range of movements after spinal cord injury. However, the mechanisms and neural structures through which EES facilitates movement execution remain unclear. Here, we designed a comp ...

Society for Neuroscience2013

Tenascin C Promiscuously Binds Growth Factors via Its Fifth Fibronectin Type III-Like Domain

Jeffrey Alan Hubbell, Federico Tortelli, Jeffrey James Rice

Tenascin C (TNC) is an extracellular matrix protein that is upregulated during development as well as tissue remodeling. TNC is comprised of multiple independent folding domains, including 15 fibronectin type III-like (TNCIII) domains. The fifth TNCIII dom ...

Public Library of Science2013

Specific Notch receptor-ligand interactions control human TCR-alpha beta/gamma delta development by inducing differential Notch signal strength

Freddy Radtke, Ute Koch, Tao Wang

In humans, high Notch activation promotes gamma delta T cell development, whereas lower levels promote alpha beta-lineage differentiation. How these different Notch signals are generated has remained unclear. We show that differential Notch receptor-ligand ...

Rockefeller University Press2013

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Crête neurale

A Subpopulation of Smooth Muscle Cells, Derived from Melanocyte-Competent Precursors, Prevents Patent Ductus Arteriosus

Cooperative Roles of SDF-1 alpha and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

Age-related cognitive impairments in mice with a conditional ablation of the neural cell adhesion molecule

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

Virtual reality based Brain-Machine-Interface for Sensori-Motor and Social experiments with Primates

Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

A Computational Model for Epidural Electrical Stimulation of Spinal Sensorimotor Circuits

Tenascin C Promiscuously Binds Growth Factors via Its Fifth Fibronectin Type III-Like Domain

Specific Notch receptor-ligand interactions control human TCR-alpha beta/gamma delta development by inducing differential Notch signal strength

Graph Chatbot

Chattez avec Graph Search

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

A Computational Model for Epidural Electrical Stimulation of Spinal Sensorimotor Circuits

A Subpopulation of Smooth Muscle Cells, Derived from Melanocyte-Competent Precursors, Prevents Patent Ductus Arteriosus

Cooperative Roles of SDF-1 alpha and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

Tenascin C Promiscuously Binds Growth Factors via Its Fifth Fibronectin Type III-Like Domain

Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

Age-related cognitive impairments in mice with a conditional ablation of the neural cell adhesion molecule

Virtual reality based Brain-Machine-Interface for Sensori-Motor and Social experiments with Primates

Specific Notch receptor-ligand interactions control human TCR-alpha beta/gamma delta development by inducing differential Notch signal strength