Concept

Mitose

Publications associées (181)

The S-pombe cytokinesis NDR kinase Sid2 activates Fin1 NIMA kinase to control mitotic commitment through Pom1/Wee1

Mitotic exit integrates the reversal of the phosphorylation events initiated by mitotic kinases with a controlled cytokinesis event that cleaves the cell in two. The mitotic exit network (MEN) of budding yeast regulates both processes, whereas the fission ...

Nature Publishing Group2012

Cortical dynein is critical for proper spindle positioning in human cells

Pierre Gönczy, Coralie Busso, Sachin Kotak

Correct spindle positioning is fundamental for proper cell division during development and in stem cell lineages. Dynein and an evolutionarily conserved ternary complex (nuclear mitotic apparatus protein [NuMA]–LGN–Gα in human cells and LIN-5–GPR-1/2–Gα in ...

Rockefeller Univ Press2012

Towards understanding HsSAS-6, a key player in centriole duplication

Debora Keller

The centrosome is the cell’s main microtubule organizing center. In order to assemble a proper bipolar spindle in mitosis, the cell has to duplicate its inherited single centrosome. During centrosome duplication, a single procentriole assembles approximate ...

EPFL2012

Nonlinear plasmonics of metallic heptamers

Olivier Martin, Krishnan Thyagarajan, Simon Rivier

Second-harmonic generation (SHG) from centrosymmetric nanostructures originating from the breaking of inversion symmetry at their surfaces is a well-known phenomenon and is extensively used as a surface probe in nonlinear optical microscopy. In recent year ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2012

Dividing the spoils of growth and the cell cycle: The fission yeast as a model for the study of cytokinesis

Viesturs Simanis, Anupama Goyal

Cytokinesis is the final stage of the cell cycle, and ensures completion of both genome segregation and organelle distribution to the daughter cells. Cytokinesis requires the cell to solve a spatial problem (to divide in the correct place, orthogonally to ...

2011

A New Hybrid Bayesian-Variational Particle Filter With Application To Mitotic Cell Tracking

Michaël Unser, Ricard Delgado Gonzalo

Tracking algorithms are traditionally based on either a variational approach or a Bayesian one. In the variational case, a cost function is established between two consecutive frames and minimized by standard optimization algorithms. In the Bayesian case, ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2011

A New Hybrid Bayesian-Variational Particle Filter with Application to Mitotic Cell Tracking

Michaël Unser, Ricard Delgado Gonzalo

IEEE2011

The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication

Pierre Gönczy, Debora Keller

Deregulated centrosome duplication can result in genetic instability and contribute to tumorigenesis(1,2). Here, we show that centrosome duplication is regulated by the activity of an E3-ubiquitin ligase that employs the F-box protein FBXW5 (ref. 3) as its ...

Nature Publishing Group2011

Mitotic Catastrophe Occurs in the Absence of Apoptosis in p53-Null Cells with a Defective G1 Checkpoint

Peter Martin Beard, Michail Fragkos

Cell death occurring during mitosis, or mitotic catastrophe, often takes place in conjunction with apoptosis, but the conditions in which mitotic catastrophe may exhibit features of programmed cell death are still unclear. In the work presented here, we st ...

Public Library of Science2011

Plasmodium falciparum NIMA-related kinase Pfnek-1: sex specificity and assessment of essentiality for the erythrocytic asexual cycle

The Plasmodium falciparum kinome includes a family of four protein kinases (Pfnek-1 to -4) related to the NIMA (never-in-mitosis) family, members of which play important roles in mitosis and meiosis in eukaryotic cells. Only one of these, Pfnek-1, which we ...

2011

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