Concept

Transfert horizontal de gènes

Publications associées (176)

Effect of cetyltrimethylammonium chloride on various Escherichia coli strains and their inactivation kinetics by ozone and monochloramine

Urs von Gunten, Florian Frédéric Vincent Breider, Margaux Océane Voumard

Cethyltrimethylammonium chloride (CTMA) is one of the most used quaternary ammonium compounds (QACs) in consumer products. CTMA and other QACs are only partially eliminated in municipal wastewater treatment and they can interact with bacteria in biological ...

2022

High Aspect Ratio Au Microflakes via Gap-Assisted Synthesis

Giulia Tagliabue, Fateme Kiani Shahvandi

Ultrathin and extra-large single-crystalline Au microflakes (Au MFs) have a huge potential in applications ranging from nanophotonics to catalysis. Yet, wet chemical synthesis approaches cannot access this size range due to the proportionality between grow ...

AMER CHEMICAL SOC2022

The Dynamics of Single-Cell Nanomotion Behaviour of Saccharomyces cerevisiae in a Microfluidic Chip for Rapid Antifungal Susceptibility Testing

Sandor Kasas, María Inés Villalba

The fast emergence of multi-resistant pathogenic yeasts is caused by the extensive-and sometimes unnecessary-use of broad-spectrum antimicrobial drugs. To rationalise the use of broad-spectrum antifungals, it is essential to have a rapid and sensitive syst ...

MDPI2022

Pilus production in Acinetobacter baumannii is growth phase dependent and essential for natural transformation

Melanie Blokesch, Nina Vesel

Acinetobacter baumannii is a severe threat to human health as a frequently multidrug-resistant hospital-acquired pathogen. Part of the danger from this bacterium comes from its genome plasticity and ability to evolve quickly by taking up and recombining ex ...

2021

A New Chemoenzymatic Semisynthetic Approach Provides Insight into the Role of Phosphorylation beyond Exon1 of Huntingtin and Reveals N-Terminal Fragment Length-Dependent Distinct Mechanisms of Aggregation

Hilal Lashuel, Jonathan Jean-Pierre Ricci, Andreas Reif, Iman Rostami, Rajasekhar Kolla, Gopinath Pushparathinam

Huntington’s disease is a neurodegenerative dis- order caused by the expansion of a polyglutamine repeat (>36Q) in the N-terminal domain of the huntingtin protein (Htt), which renders the protein or fragments thereof more prone to aggregate and form inclus ...

2021

KRAB zinc finger protein-mediated control of transposon-embedded regulatory sequences from human germline to early embryos

Alexandra Iouranova

Transposable elements (TEs), also called jumping genes, are genetic elements capable of changing their position within the genome of their host. They make up large fractions of genomes, including 45% of human DNA content, according to current estimates. S ...

EPFL2021

Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates

Hilal Lashuel, Anass Chiki

Huntington's disease (HD) is caused by a CAG trinucleotide repeat expansion in the first exon of the huntingtin (HTT) gene coding for the huntingtin (HTT) protein. The misfolding and consequential aggregation of CAG-expanded mutant HTT (mHTT) underpin HD p ...

NATURE PORTFOLIO2021

Microdiversity characterizes prevalent phylogenetic clades in the glacier-fed stream microbiome

Tom Ian Battin, Hannes Markus Peter, Susheel Bhanu Busi, Massimo Bourquin, Tyler Joe Kohler, Jade Brandani, Stylianos Fodelianakis, Paraskevi Pramateftaki, Vincent Henri De Staercke, Matteo Tolosano, Michail Styllas

Glacier-fed streams (GFSs) are extreme and rapidly vanishing ecosystems, and yet they harbor diverse microbial communities. Although our understanding of the GFS microbiome has recently increased, we do not know which microbial clades are ecologically succ ...

SPRINGERNATURE2021

Working on mobility from people

Vincent Kaufmann

Describing, understanding, explaining and regulating mobility requires transversal approaches. Traditionally, mobility analysis proceeds by partitioning into four differentiated forms according to two dimensions: the temporality of which it is based and th ...

Routledge2021

Retention of E. coli and water on the skin after liquid contact

Tamar Kohn, Timothy R. Julian

The frequent contact people have with liquids containing pathogenic microorganisms provides opportunities for disease transmission. In this work, we quantified the transfer of bacteria—using E. coli as a model- from liquid to skin, estimated liquid retenti ...

2020

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