Concept

Guidage axonal

Publications associées (125)

White matter maturation reshapes structural connectivity in the late developing human brain

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Leila Cammoun, Olaf Sporns, Van Jay Wedeen

From toddler to late teenager, the macroscopic pattern of axonal projections in the human brain remains largely unchanged while undergoing dramatic functional modifications that lead to network refinement. These functional modifications are mediated by inc ...

National Academy of Sciences2010

Prematurity and prenatal growth restriction differently affects brain connectivity at age 6 years.

Jean-Philippe Thiran, Elda Fischi Gomez, Reto Meuli, Patric Hagmann, Djalel Eddine Meskaldji, Leila Cammoun, François Lazeyras

Survival of children born prematurely or with very low birth weight has increased dramatically but the long term developmental outcome remains a concern with many children having deficits in their cognitive capacities, in particular involving executive dom ...

2010

Evolution amplified processing with temporally dispersed slow neuronal connectivity in primates

Hassan Ghaziri, Giorgio Innocenti

The corpus callosum (CC) provides the main route of communication between the 2 hemispheres of the brain. In monkeys, chimpanzees, and humans, callosal axons of distinct size interconnect functionally different cortical areas. Thinner axons in the genu and ...

National Academy of Sciences2009

Global brain connectivity analysis by diffusion MR tractography

Xavier Gigandet

The human cerebral cortex consists of approximately 1010 neurons that are organized into a complex network of local circuits and long-range connections. During the past years there has been an increasing interest from the neuro-scientific community towards ...

EPFL2009

Predicting Human Resting-State Functional Connectivity from structural Connectivity

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Leila Cammoun, Xavier Gigandet, Olaf Sporns

In the cerebral cortex, the activity levels of neuronal populations are continuously fluctuating. When neuronal activity, as measured using functional MRI (fMRI), is temporally coherent across 2 populations, those populations are said to be functionally co ...

2009

A Microfluidic Device to Study Axon Growth and Guidance

Sarra de Valence

[...] Studying axon guidance by diffusible or substrate bound gradients is challenging with current techniques. In this study, we present two microfluidic devices to study axon guidance. [... click on "Download fulltext" for full abstract] ...

2008

Modified Trans-synaptic Tracing Viruses Reveal Novel Connectivity in the Rat Olfactory Bulb

Aurélie Pala

Olfaction and the olfactory pathway is a good system to study sensory processing in general, mainly because of the simplified organization of the cells constituting the olfactory bulb, the anatomical structure responsible for early odor encoding and proces ...

2008

A Neural Model of Demyelination of the Mouse Spinal Cord

Biljana Petreska von Ritter-Zahony

This paper presents a neural network model of demyelination of the mouse motor pathways, coupled to a central pattern generation (CPG) model for quadruped walking. Demyelination is the degradation of the myelin layer covering the axons which can be caused ...

2008

The Structural Core of Human Cerebral Cortex and its relation to the brain s default network

Reto Meuli, Leila Cammoun, Xavier Gigandet, Olaf Sporns

Human cerebral cortex contains an uncertain number of structurally segregated regions interconnected by a dense network of axonal pathways. Using DSI, we map these pathways in individual human subjects. An analysis of the resulting large-scale structural b ...

2008

Evolutionary and Computational Advantages of Neuromodulated Plasticity

Andrea Soltoggio

The integration of modulatory neurons into evolutionary artificial neural networks is proposed here. A model of modulatory neurons was devised to describe a plasticity mechanism at the low level of synapses and neurons. No initial assumptions were made on ...

University of Birmingham, UK2008

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