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Sporozoites, the invasive form of malaria parasites transmitted by mosquitoes, are quiescent while in the insect salivary glands. Sporozoites only differentiate inside of the hepatocytes of the mammalian host. We show that sporozoite latency is an active p ...
Rockefeller University Press2010
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We present a portable microsystem to quantitatively detect cocaine in human saliva. The chip combines a simple microfluidic method for multiphase liquid-liquid extraction to transfer cocaine from IR-light absorbing saliva to an IRtransparent solvent with t ...
2012
P>The role of fat content and type of surfactant for oral friction processes and texture perception of oil-in-water emulsions was assessed. Emulsions at 22% and 33% fat content containing either sodium caseinate or a sucrose ester as emulsifier were compar ...
2009
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The proteins belonging to the WhiB superfamily are small global transcriptional regulators typical of actinomycetes. In this paper, we characterize the role of WhiB5, a Mycobacterium tuberculosis protein belonging to this superfamily. A null mutant was con ...
Osteoarthritis (OA) is one of the most common causes of pain and disability. Currently, non-surgical treatment is limited to analgesic and anti-inflammatory drugs, which are not capable of either modifying the disease process or regenerate damaged parts in ...
A Si/Ge based, single mode, mid-infrared optical waveguide, is used as an evanescent sensor in liquid matrix. The selectivity is achieved by the use of quantum cascade lasers (QCLs) tuned to the maximum absorption of a given analyte. The cocaine detection ...
The efficiency of on-chip microfluidic liquid-liquid extraction was improved by two orders of magnitude by spraying one liquid in another compared to the state-of-the-H-filters. We are developing a portable, integrated optical microsystem in the mid-infrar ...
The role of the Notch signaling members Notch1, Notch2 and Rbpj in exocrine pancreatic development is not well defined. We therefore analyzed conditional pancreas-specific Rbpj and combined Notch1/Notch2 knockout mice using Ptf1a(+/Cre(ex1)) mice crossed w ...
2008
Cancer: growth caused by uncontrolled and abnormal cell division, resulting in a non-structured mass or tumor, serving no beneficial purpose to the body. Even though cancer is one of the leading fatal diseases of today's world, with no distinction for age, ...
Beta-catenin signaling is heavily involved in organogenesis. Here, we investigated how pancreas differentiation, growth and homeostasis are affected following inactivation of an endogenous inhibitor of beta-catenin, adenomatous polyposis coli (Apc). In adu ...
