Concept

Invasive carcinoma of no special type

Publications associées (35)

GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer

Bart Deplancke, Natasha Ella Samson, Etienne Meylan, Petra Catalina Schwalie, Svenja Johanna Groeneveld, Jessica Christine Vazquez, Mark Jonathan Masin

Alterations in glucose metabolism and epithelial-mesenchymal transition (EMT) constitute two important characteristics of carcinoma progression toward invasive cancer. Despite an extensive characterization of each of them separately, the links between EMT ...

2014

Microfluidic processor allows rapid HER2 immunohistochemistry of breast carcinomas and significantly reduces ambiguous (2+) read-outs

Martinus Gijs, Ata Tuna Ciftlik, Hans-Anton Lehr

Biomarker analysis is playing an essential role in cancer diagnosis, prognosis, and prediction. Quantitative assessment of immunohistochemical biomarker expression on tumor tissues is of clinical relevance when deciding targeted treatments for cancer patie ...

National Academy of Sciences2013

Opportunities for high-pressure microfluidics in biomedical applications

Ata Tuna Ciftlik

Pressure lies at the basis of operation of most microfluidic systems, and is a determinant factor in the extent of miniaturization and in limiting the throughput and time constant of the microfluidic assays. Despite the apparent importance given to fluidic ...

EPFL2013

Understanding the Challenges of Adjuvant Treatment Measurement and Reporting in Breast Cancer Cancer Treatment Measuring and Reporting

Background: Healthcare accrediting organizations and insurers increasingly require reporting of clinical data, and cancer treatment is one area of enhanced scrutiny. Objectives: To compare rates of received versus reported adjuvant breast cancer treatments ...

Lippincott Williams & Wilkins2013

ER and PR signaling nodes during mammary gland development

Cathrin Brisken, Tamara Tanos, Lucia Jimenez Rojo

The ovarian hormones estrogen and progesterone orchestrate postnatal mammary gland development and are implicated in breast cancer. Most of our understanding of the molecular mechanisms of estrogen receptor (ER) and progesterone receptor (PR) signaling ste ...

BioMed Central2012

Synthesis of Glycomimetics as Potential Anti-Cancer Agents

Annabelle Gillig

Cancer cells exhibit different properties that make them dangerous to the host, such as the ability to invade other tissues and the abnormal response to the control mechanisms that regulate the division of normal cells, which allow them to divide in a rela ...

EPFL2010

Optimisation d’un actionneur biomédical

Sebastiano Merzaghi

L’optimisation d’un actionneur biomédical permettant la mesurer du taux de glycémie par une méthode non invasive, représente l’objectif de ce travail de Master. Cet actionneur a été conçu à partir du principe de fonctionnement des moteurs synchrones. ...

2006

Identification of molecular apocrine breast tumours by microarray analysis

Cathrin Brisken, Darlene Goldstein, Maryse Fiche

Previous microarray studies on breast cancer identified multiple tumour classes, of which the most prominent, named luminal and basal, differ in expression of the oestrogen receptor alpha gene (ER). We report here the identification of a group of breast tu ...

2005

Insulin-like growth factor-II bound to vitronectin enhances MCF-7 breast cancer cell migration

Christopher Towne

We have previously reported that IGF-II binds the extracellular matrix protein vitronectin (VN) with an affinity similar to that for the type-1 IGF receptor (IGF-1R). In view of this finding, and given the cited role of VN in cell motility and adhesion, we ...

2003

A chromosome 3-encoded repressor of the human telomerase reverse transcriptase (hTERT) gene controls the state of hTERT chromatin

Joachim Lingner

Telomerase is crucial for human carcinogenesis. The limiting component of telomerase activity is telomerase reverse transcriptase (hTERT), undetectable in differentiated somatic cells but present in most tumor cells. There is evidence that hTERT transcript ...

2003

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