Concept
Hill equation (biochemistry)
Publications associées (21)
Nb, Ta and Hf-The tri-dopant tournament for the enhancement of TiO2 photochromism
TiO2 quantum dot (QD) size nanoparticle colloids have shown tremendous photochromic response. Here we show that the of the photochromic response of TiO2 QDs can be further enhanced by doping. Our synthesis approach allows to reach high nominal doping level ...
ELSEVIER SCIENCE SA2023Systematic analysis of biomolecular binding reactions using microfluidic systems
Transcription factor binding to a single binding site on DNA and its functional consequence in a promoter context are beginning to be relatively well understood. However, binding to clusters of sites has yet to be characterized in depth, and the functional ...
EPFL2022Mechanics of Allostery: Contrasting the Induced Fit and Population Shift Scenarios
Matthieu Wyart, Carolina Brito Carvalho dos Santos, Solange Marie Flatt, Stefano Zamuner, Riccardo Ravasio
In allosteric proteins, binding a ligand can affect function at a distant location, for example, by changing the binding affinity of a substrate at the active site. The induced fit and population shift models, which differ by the assumed number of stable c ...
CELL PRESS2019A ligand-based system for receptor-specific delivery of proteins
Gene delivery using vector or viral-based methods is often limited by technical and safety barriers. A promising alternative that circumvents these shortcomings is the direct delivery of proteins into cells. Here we introduce a non-viral, ligand-mediated p ...
Springer2019Real-time binding kinetics of ligand-receptor interactions
In principle, a major goal in drug development is to design a high-affinity compound with an appropriate pharmacological response, which requires understanding of physical processes underlying the drug-target interaction, affinity and specificity. This dru ...
EPFL2017