Concept

Lipid bilayer fusion

Publications associées (233)

Role of Protein Kinase C and Munc18-1 in a Presynaptic Form of Plasticity, Post-tetanic Potentiation

Neurons are arranged in networks in which they communicate between each other by the means of synapses. Synaptic transmission can undergo activity-dependent and short-lived changes in strength, known as short-term synaptic plasticity. Short-term plasticity ...

EPFL2013

New Eyes on Existing Buildings

Marilyne Andersen

On May 15-16, 2013 the 5th International Daylight Symposium, themed « New Eyes on Existing Buildings » and organized by Velux, took place at the Royal Academy of Arts in Copenhagen, Denmark. It was preceded by the 2nd Academic Forum for PhD students workin ...

2013

Molecular Modeling of Membrane Embedded Proteins

Thomas Lemmin

Over the past years, molecular modeling and simulation techniques have had a major impact on experimental life sciences. They are capable of providing accurate insight into microscopic mechanisms, which are usually difficult to investigate experimentally. ...

EPFL2013

Cardiolipin Models for Molecular Simulations of Bacterial and Mitochondrial Membranes

Matteo Dal Peraro, Diane Virginie Marie Lançon, Thomas Lemmin, Christophe Bovigny

Present in bacterial and mitochondrial membranes, cardiolipins have a unique dimeric structure, which carries up to two charges (i.e., one per phosphate group) and, under physiological conditions, can be unprotonated or singly protonated. Exhaustive models ...

Amer Chemical Soc2013

On the Equivalence of Schemes for Simulating Bilayers at Constant Surface Tension

Berend Smit

Lipid bilayers are simulated using flexible simulation cells in order to allow for relaxations in area per lipid as bilayer content and temperature are varied. We develop a suite of Monte Carlo (MC) moves designed to generate constant surface tension γ and ...

2012

Phage Pierces the Host Cell Membrane with the Iron-Loaded Spike

Petr Leiman, Christopher Browning

Bacteriophages with contractile tails and the bacterial type VI secretion system have been proposed to use a special protein to create an opening in the host cell membrane during infection. These proteins have a modular architecture but invariably contain ...

2012

Oriented CoSAPO-5 membranes by microwave-enhanced growth on TiO2-coated porous alumina

Kumar Varoon Agrawal, Xu Zhang

Microwaving plates: A facile method was developed for the fabrication of preferentially c-oriented cobalt-substituted silicoaluminophosphate-5 (CoSAPO-5) membranes on porous alumina supports. In situ microwave growth using a slip-coated TiO 2 layer on the ...

2012

A Biochemical and Biophysical Investigation of 5-HT3 Receptor Stability

Menno Berend Tol

The 5-hydroxytryptamine 3 receptor (5-HT3R) is a member of the pentameric ligand-gated ion channel (pLGIC) family, that plays an important role in fast signal transduction and cell-cell communication in synapses: They convert a chemical signal from a neuro ...

EPFL2012

Connecting vesicular transport with lipid synthesis: FAPP2

Giovanni D'Angelo

Next to the protein-based machineries composed of small G-proteins, coat complexes, SNAREs and tethering factors, the lipid-based machineries are emerging as important players in membrane trafficking. As a component of these machineries, lipid transfer pro ...

2012

Dynamic Cellular Uptake of Mixed-Monolayer Protected Nanoparticles

Francesco Stellacci, Randy Patrick Carney, Tamara Michael Carney, Marie Mueller

Nanoparticles (NPs) are gaining increasing attention for potential application in medicine; consequently, studying their interaction with cells is of central importance. We found that both ligand arrangement and composition on gold nanoparticles play a cru ...

American Vacuum Society2012

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