Concept

Nanomédecine

Publications associées (165)

Free-electron-laser coherent diffraction images of individual drug-carrying liposome particles in solution

Giorgio Margaritondo, Ying Chen, Ke Peng

Using the excellent performances of a SACLA (RIKEN/HARIMA, Japan) X-ray free electron laser (X-FEL), coherent diffraction imaging (CDI) was used to detect individual liposome particles in water, with or without inserted doxorubicin nanorods. This was possi ...

2018

Free-electron-laser coherent diffraction images of individual drug-carrying liposome particles in solution

Giorgio Margaritondo, Ke Peng

2018

Evaluating the Critical Roles of Precursor Nature and Water Content When Tailoring Magnetic Nanoparticles for Specific Applications

Assil Bouzid, Carlo Massobrio

Because of the broad range of application of iron oxide nanoparticles (NPs), the control of their size and shape on demand remains a great challenge, as these parameters are of upmost importance to provide NPs with magnetic properties tailored to the targe ...

AMER CHEMICAL SOC2018

Fluorescence Imaging For Ultrafiltration Of Individual Nanoparticles From A Colloidal Solution In Track Membranes

We have used fluorescence nanoscopy for direct imaging of adsorption of individual colloidal quantum dots of diameter similar to 10 nm (spherical core/shell CdSeS/ZnS semiconductor nanocrystals, functionalized by organic oleic acid ligands) in nanopores of ...

2018

Synthesis and Postpolymerization Modification of Fluorine-End-Labeled Poly(Pentafluorophenyl Methacrylate) Obtained via RAFT Polymerization

Harm-Anton Klok, Jie Chen, Claudia Battistella

Chain-end-labeled polymers are interesting for a range of applications. In polymer nanomedicine, chain-end-labeled polymers are useful to study and help understand cellular internalization and intracellular trafficking processes. The recent advent of fluor ...

2018

Xeno Nucleic Acid Nanosensors for Enhanced Stability Against Ion-Induced Perturbations

Ardemis Anoush Boghossian, Carlo Gigli, Alice Judith Gillen, Justyna Kupis-Rozmyslowicz

The omnipresence of salts in biofluids creates a pervasive challenge in designing sensors suitable for in vivo applications. Fluctuations in ion concentrations have been shown to affect the sensitivity and selectivity of optical sensors based on single-wal ...

2018

Controlling and Monitoring Intracellular Delivery of Anticancer Polymer Nanomedicines

Harm-Anton Klok, Claudia Battistella

Polymer nanomedicines are very attractive to improve the delivery of chemotherapeutics. Polymer conjugates and other polymer-based nanocarriers allow to increase plasma half-life and drug bioavailability and can also be guided toward tumors using passive a ...

2017

Superplastic behavior of silica nanowires obtained by direct patterning of silsesquioxane-based precursors

Yusuf Leblebici, Mohammad Nasr Esfahani, Mustafa Yilmaz

Silica nanowires spanning 10 μm-deep trenches are fabricated from different types of silsesquioxane-based precursors by direct e-beam patterning on silicon followed by release through deep reactive ion etching. Nanowire aspect ratios as large as 150 are ac ...

Institute of Physics2017

High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry

Francesco Stellacci, Li Tang, Ye Yang, Ahmet Bekdemir

Inorganic nanoparticles (NPs) are studied as drug carriers, radiosensitizers and imaging agents, and characterizing nanoparticle biodistribution is essential for evaluating their efficacy and safety. Tracking NPs at the single-cell level with current techn ...

Nature Publishing Group2017

Controlling and Monitoring Intracellular Drug Delivery Using PHPMA-Based Polymer Nanomedicines

Claudia Battistella

Polymer nanomedicine is an attractive approach for the delivery of anticancer drugs. Firstly designed to increase drug bioavailability, polymer conjugates and polymer nanoparticles have rapidly emerged in the field of cancer therapy after the discovery of ...

EPFL2017

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