Publications associées à Interaction protéine-protéine

Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor

Maria Josefina Marcaida Lopez, Michele Cascella, Christos Lamprakis

We present the crystal structures of the SEC14-like domain of supernatant protein factor (SPF) in complex with squalene and 2,3-oxidosqualene. The structures were resolved at 1.75 angstrom (complex with squalene) and 1.6 angstrom resolution (complex with 2 ...

Academic Press Inc Elsevier Science2015

Probing fibronectin-antibody interactions using AFM force spectroscopy and lateral force microscopy

Andrzej Kulik, Kyumin Lee

The first experiment showing the effects of specific interaction forces using lateral force microscopy (LFM) was demonstrated for lectin-carbohydrate interactions some years ago. Such measurements are possible under the assumption that specific forces stro ...

Beilstein-Institut2015

Relevance of the Drag Force during Controlled Translocation of a DNA–Protein Complex through a Glass Nanocapillary

Aleksandra Radenovic, Sanjin Marion, Roman Bulushev

Combination of glass nanocapillaries with optical tweezers allowed us to detect DNA-protein complexes in physiological conditions. In this system, a protein bound to DNA is characterized by a simultaneous change of the force and ionic current signals from ...

American Chemical Society2015

Understanding Small-Molecule Interactions in Metal-Organic Frameworks: Coupling Experiment with Theory

Berend Smit, Wendy Lee Queen

Metal-organic frameworks (MOFs) have gained much attention as next-generation porous media for various applications, especially gas separation/storage, and catalysis. New MOFs are regularly reported; however, to develop better materials in a timely manner ...

Wiley-Blackwell2015

GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis

Stewart Cole, Matteo Dal Peraro, Luciano Andres Abriata, Claudia Sala, Gaëlle Séraphine Kolly, Mahé Cécile Raccaud, Raju Mukherjee

Mycobacterium tuberculosis possesses a thick and highly hydrophobic cell wall principally composed of a mycolyl-arabinogalactan-peptidoglycan complex, which is critical for survival and virulence. DprE1 is a well-characterized component of decaprenyl-phosp ...

Amer Soc Microbiology2015

The centriolar protein CPAP G-box: an amyloid fibril in a single domain

Georgios Hatzopoulos

Centrioles are evolutionarily conserved cylindrical cell organelleswith characteristic radial symmetry. Despite their considerable size (400 nm x 200 nm, in humans), genetic studies suggest that relatively few protein components are involved in their assem ...

Portland Press Ltd2015

Hyperpolarized Water to Study Protein-Ligand Interactions

Geoffrey Bodenhausen, Aurélien Bornet, Sami Jannin, Jonas Milani, Basile Vuichoud, Quentin Chappuis

The affinity between a chosen target protein and small molecules is a key aspect of drug discovery. Screening by popular NMR methods such as Water-LOGSY suffers from low sensitivity and from false positives caused by aggregated or denatured proteins. This ...

2015

Abrogation of HMX1 Function Causes Rare Oculoauricular Syndrome Associated With Congenital Cataract, Anterior Segment Dysgenesis, and Retinal Dystrophy

PURPOSE. To define the phenotypic manifestation, confirm the genetic basis, and delineate the pathogenic mechanisms underlying an oculoauricular syndrome (OAS). METHODS. Two individuals from a consanguineous family underwent comprehensive clinical phenotyp ...

Assoc Research Vision Ophthalmology Inc2015

A mammalian transcription factor-specific peptide repository for targeted proteomics

Bart Deplancke, Romain Hamelin, Marc Moniatte, Jovan Simicevic

Site-specific transcription factors (TFs) play an essential role in mammalian development and function as they are vital for the majority of cellular processes. Despite their biological importance, TF proteomic data is scarce in the literature, likely due ...

Wiley-Blackwell2015

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Interaction protéine-protéine

Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor

Probing fibronectin-antibody interactions using AFM force spectroscopy and lateral force microscopy

Relevance of the Drag Force during Controlled Translocation of a DNA–Protein Complex through a Glass Nanocapillary

Dynamic structure and protein expression of the live embryonic heart captured by 2-photon light sheet microscopy and retrospective registration

Understanding Small-Molecule Interactions in Metal-Organic Frameworks: Coupling Experiment with Theory

GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis

The centriolar protein CPAP G-box: an amyloid fibril in a single domain

Hyperpolarized Water to Study Protein-Ligand Interactions

Abrogation of HMX1 Function Causes Rare Oculoauricular Syndrome Associated With Congenital Cataract, Anterior Segment Dysgenesis, and Retinal Dystrophy

A mammalian transcription factor-specific peptide repository for targeted proteomics

Graph Chatbot

Chattez avec Graph Search

Hyperpolarized Water to Study Protein-Ligand Interactions

Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor

Probing fibronectin-antibody interactions using AFM force spectroscopy and lateral force microscopy

Dynamic structure and protein expression of the live embryonic heart captured by 2-photon light sheet microscopy and retrospective registration

Relevance of the Drag Force during Controlled Translocation of a DNA–Protein Complex through a Glass Nanocapillary

GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis

Understanding Small-Molecule Interactions in Metal-Organic Frameworks: Coupling Experiment with Theory

The centriolar protein CPAP G-box: an amyloid fibril in a single domain

Abrogation of HMX1 Function Causes Rare Oculoauricular Syndrome Associated With Congenital Cataract, Anterior Segment Dysgenesis, and Retinal Dystrophy

A mammalian transcription factor-specific peptide repository for targeted proteomics