Publications associées à Difluorure de dioxygène

Synthesis of C-linked Disaccharides and Analogues as Biomimetics of the TF Epitope

Glycoproteins and glycolipids are major components of the outer surface of mammalian cells. Their carbohydrate moieties, which are directed into the outer environment, serve as ligands for receptor proteins, such as lectins, pathogen proteins and antibodie ...

EPFL2011

Facile synthesis and relaxation properties of novel bispolyazamacrocyclic Gd3+ complexes: An attempt towards calcium-sensitive MRI contrast agents

Eva Jakab Toth, Anurag Mishra

Three novel GdDO3A-type bismacrocyclic complexes, conjugated to Ca2+ chelating moieties like ethylenediamine-tetraacetic acid and diethylenetriamine pentaacetic acid bisamides, were synthesized as potential "smart" magnetic resonance imaging contrast agent ...

2008

Position-flexible elaboration of halogenated heterocycles: Metalated species as key intermediates for synthesis

Halogens, in particular fluorine atoms, are favorite tools to fine-tune the chemical and biological properties of pharmaceutical or agricultural development products. At the same time, such an electronegative substituent can effectively assist the site-sel ...

2007

Fluorine-flanked congested sites: Minimal, though perceptible buttressing effects on the proton mobility of arenes

Christophe Heiss

(2,6-Difluorophenyl)trimethylsilane, -triethylsilane and -triisopropylsilane undergo sec-butyllithium-mediated metalation at the 3- and 4-position (ortho and meta relative to the halogen) in ratios of 99.6:0.4, 98:2 and 95:5, resp. The steric pressure tran ...

2005

The gas phase acidity of oligofluorobenzenes and oligochlorobenzenes: about the additivity or non-additivity of substituent effects

Fabrice Cottet

The deprotonation energies of benzene, fluorobenzene, all di-, tri-, and tetrafluorobenzenes, pentafluorobenzene, chlorobenzene, all di-, tri-, and tetrachlorobenzenes, and pentachlorobenzene have been calcd. at various levels of second-order Moller-Plesse ...

2005