Concept
Transfert d'acide ribonucléique
Publications associées (85)
An atypical mitogen-activated protein kinase (MAPK) homologue expressed in gametocytes of the human malaria parasite Plasmodium falciparum: Identification of a MAPK signature
The cDNA encoding Pfmap-2, an enzyme of the human malaria parasite Plasmodium falciparum, was cloned, sequenced, and expressed in Escherichia coli. The open reading frame carried by the Pfmap-2 cDNA encodes a 508-amino acid polypeptide of 59.2 kDa with max ...
American Society for Biochemistry and Molecular Biology1999Functionalization of the Sugar Moiety of Oligoribonucleotides on Solid Support
A solid-phase method for the introduction of a variety of different side chains into oligoribonucleotides is presented. It is based on a b-D-allofuranosyl phosphoramidite with a bromopentyl-substituent tethered to the 6'-O position. After its incorporation ...
1999VIP and PACAP potentiate the action of glutamate on BDNF expression in mouse cortical neurones
Pierre Magistretti, Jean-Luc Martin
In view of the neurotrophic effect of vasoactive intestinal peptide (VIP), the regulation of brain-derived neurotrophic factor (BDNF) expression by VIP and the related peptide pituitary adenylate cyclase-activating polypeptide (PACAP) was analysed by North ...
1998Cloning of the human puromycin-sensitive aminopeptidase and evidence for expression in neurons
The puromycin-sensitive aminopeptidase (PSA) is thought to contribute to the degradation of enkephalins. Besides being the most abundant aminopeptidase in the brain, PSA is expressed in other organs as well. From a human fetal brain cDNA library, we have i ...
Wiley-Blackwell1997The expression pattern of the mafB/kr gene in birds and mice reveals that the kreisler phenotype does not represent a null mutant
The recessive mouse mutation kreisler affects hindbrain segmentation and inner ear development in homozygous mice. The mouse gene affected by the mutation was found to encode a basic domain leucine-zipper (bZIP)-type transcription factor of the Maf-family ...
1997Central nervous system delivery of recombinant ciliary neurotrophic factor by polymer encapsulated differentiated C2C12 myoblasts
Neurotrophic factors hold promise for the treatment of neurodegenerative diseases. Intrathecal transplantation of polymer encapsulated cell lines genetically engineered to release neurotrophic factors provides a means to deliver them continuously behind th ...
1996