Concept

Tératologie

Publications associées (12)

The local strength of individual alumina particles

Andreas Mortensen, Goran Zagar, Václav Pejchal, Marta Fornabaio

We implement the C-shaped sample test method and micro-cantilever beam testing to measure the local strength of microscopic, low-aspect-ratio ceramic particles, namely high purity vapor grown a-alumina Sumicorundum (R) particles 15-30 mu m in diameter, kno ...

2017

Wireless Power Transfer and Data Communication for Intracranial Neural Implants Case Study

Gürkan Yilmaz

Recording neural activities plays an important role in numerous applications ranging from brain mapping to implementation of brain-machine interfaces (BMI) to recover lost functions or to understand the mechanisms behind the neurological disorders such as ...

EPFL2014

General developmental health in the VPA-rat model of autism

Henry Markram, Georges Khazen, Kamila Markram, Mônica Regina Favre

Autism is a neurodevelopmental condition diagnosed by impaired social interaction, abnormal communication and, stereotyped behaviors. While post-mortem and imaging studies have provided good insights into the neurobiological symptomology of autism, animal ...

Frontiers Research Foundation2013

Integrating Defect Data, Code Review Data, and Version Control Data for Defect Analysis and Prediction

Tao-Chun Lee

In this thesis, we present a new approach to integrating software system defect data: Defect reports, code reviews and code commits. We propose to infer defect types by keywords. We index defect reports into groups by the keywords found in the descriptions ...

2013

Mercury is a direct and potent γ-secretase inhibitor affecting Notch processing and development in Drosophila

Bruno Lemaitre, Patrick Fraering, Mitko Dimitrov, Takayuki Kuraishi, Isabelle Chang

Prenatal exposure to mercury causes neurodevelopmental disorders and neurological pathologies in infants, such as microcephaly and mental retardation. Despite critical importance, the molecular interactions leading to mercury toxicity are yet to be elucida ...

2011

Prematurity and prenatal growth restriction differently affects brain connectivity at age 6 years.

Jean-Philippe Thiran, Elda Fischi Gomez, Reto Meuli, Patric Hagmann, Djalel Eddine Meskaldji, Leila Cammoun, François Lazeyras

Survival of children born prematurely or with very low birth weight has increased dramatically but the long term developmental outcome remains a concern with many children having deficits in their cognitive capacities, in particular involving executive dom ...

2010

Atomistic simulations of nanometric dislocation loops in bcc tungsten

Robin Schäublin

Small dislocation loops formed from self-interstitial atoms (SIAs) are commonly found in irradiated metals. These defects signiﬁcantly inﬂuence the mechanical properties of the materials. Atomistic simulations are used to describe nanometric circular dislo ...

Elsevier2009

Isolation and in vitro chondrogenic potential of human fetal spine cells

Dominique Pioletti, Corinne Scaletta, Sandra Jaccoud, Aurélie Quintin

Cell therapy for nucleus pulposus regeneration is an attractive treatment for early disc degeneration as shown by studies using autologous nucleus pulposus cells or stem cells. Another potential source of cells is fetal cells. We investigated the feasibili ...

2009

Hyperconnectivity of Local Neocortical Microcircuitry Induced by Prenatal Exposure to Valproic Acid

Henry Markram, Gilad Silberberg, Tania Rinaldi

Exposure to valproic acid (VPA) during embryogenesis can cause several teratogenic effects, including developmental delays and in particular autism in humans if exposure occurs during the third week of gestation. We examined the postnatal effects of embryo ...

Oxford University Press2008

Early stages of radiation damage in graphite and carbon nanostructures: A first-principles molecular dynamics study

Ursula Röthlisberger, Lothar Helm, Oleg Yazyev, Ivano Tavernelli

Understanding radiation-induced defect formation in carbon materials is crucial for nuclear technology and for the manufacturing of nanostructures with desired properties. Using first-principles molecular dynamics, we perform a systematic study of the none ...

2007

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