Publications associées à Tératologie

The local strength of individual alumina particles

Andreas Mortensen, Goran Zagar, Václav Pejchal, Marta Fornabaio

We implement the C-shaped sample test method and micro-cantilever beam testing to measure the local strength of microscopic, low-aspect-ratio ceramic particles, namely high purity vapor grown a-alumina Sumicorundum (R) particles 15-30 mu m in diameter, kno ...

2017

General developmental health in the VPA-rat model of autism

Henry Markram, Kamila Markram, Georges Khazen, Mônica Regina Favre

Autism is a neurodevelopmental condition diagnosed by impaired social interaction, abnormal communication and, stereotyped behaviors. While post-mortem and imaging studies have provided good insights into the neurobiological symptomology of autism, animal ...

Frontiers Research Foundation2013

Mercury is a direct and potent γ-secretase inhibitor affecting Notch processing and development in Drosophila

Bruno Lemaitre, Patrick Fraering, Mitko Dimitrov, Takayuki Kuraishi, Isabelle Chang

Prenatal exposure to mercury causes neurodevelopmental disorders and neurological pathologies in infants, such as microcephaly and mental retardation. Despite critical importance, the molecular interactions leading to mercury toxicity are yet to be elucida ...

2011

Atomistic simulations of nanometric dislocation loops in bcc tungsten

Robin Schäublin

Small dislocation loops formed from self-interstitial atoms (SIAs) are commonly found in irradiated metals. These defects signiﬁcantly inﬂuence the mechanical properties of the materials. Atomistic simulations are used to describe nanometric circular dislo ...

Elsevier2009

Hyperconnectivity of Local Neocortical Microcircuitry Induced by Prenatal Exposure to Valproic Acid

Henry Markram, Gilad Silberberg, Tania Rinaldi

Exposure to valproic acid (VPA) during embryogenesis can cause several teratogenic effects, including developmental delays and in particular autism in humans if exposure occurs during the third week of gestation. We examined the postnatal effects of embryo ...

Oxford University Press2007