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Publications associées (40)

Shear stress and cyclic circumferential stretch, but not pressure, alter connexin43 expression in endothelial cells

Hemodynamic forces play a critical role in atherogenesis, as evidenced by the focal pattern of development of atherosclerotic lesions. Whereas disturbed flow in the branches and curved regions of large arteries is proatherogenic, laminar flow in the straig ...

2006

Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth

Matthias Lütolf, Jeffrey Alan Hubbell, Martin Ehrbar

Local, controlled induction of angiogenesis remains a challenge that limits tissue engineering approaches to replace or restore diseased tissues. We present a new class of bioactive synthetic hydrogel matrices based on poly(ethylene glycol) (PEG) and synth ...

2003

PPAR-alpha effects on the heart and other vascular tissues

Johan Auwerx

Peroxisome proliferator-activated receptor (PPAR)-alpha is a member of a large nuclear receptor superfamily whose main role is to activate genes involved in fatty acid oxidation in the liver, heart, kidney, and skeletal muscle. While currently used mainly ...

2003

A new drug-screening procedure for photosensitizing agents used in photodynamic therapy for CNV

Hubert van den Bergh, Georges Wagnières

Because vascular occlusion has been observed as a consequence of photodynamic therapy (PDT), this method has been successfully used for the treatment of choroidal neovascularization (CNV) in age-related macular degeneration (AMD). However, most conventiona ...

2001

Relationships among testate amoebae (Protozoa), vegetation and water chemistry in five Sphagnum-dominated peatlands in Europe

Alexandre Buttler, Edward Mitchell

To study the relationships between groups of organisms and the degree to which these relationships are consistent across major climatic gradients, we analysed the testate amoeba (Protozoa) communities, vegetation and water chemistry of one peatland in five ...

2000

Size and form in efficient transportation networks

Andrea Rinaldo, Amos Maritan

Many biological processes, from cellular metabolism to population dynamics, are characterized by allometric scaling (power-law) relationships between size and rate(1-10). An outstanding question is whether typical allometric scaling relationships-the power ...

1999

SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish

Andrew Charles Oates

SCL/Tal-1 is a transcription factor necessary for hematopoietic stem cell differentiation. Although SCL is also expressed in endothelial and neural progenitors, SCL function in these cells remains unknown. In the zebrafish mutant cloche (clo), SCL expressi ...

1998

Development of Sphagnum fallax diaspores on bare peat with implications for the restoration of cut-over bogs

Alexandre Buttler

1, The growth of Sphagnum fallax was studied in a glasshouse experiment. Capitulum diaspores of S. fallax were cultivated on five different types of bare peat core, representing a gradient of increasing disturbance. Increases in length and weight were meas ...

1998

High- and low-affinity binding sites for vasoactive intestinal peptide (VIP) in the rat kidney revealed by light microscopic autoradiography

Pierre Magistretti, Jean-Luc Martin

The distribution of VIP binding sites in rat kidney and adrenal gland has been examined by light microscopic autoradiography. A fully characterized mono-iodinated molecular form of VIP (M-125-I-VIP) which maintains the biological activity of the native pep ...

1988

Community patterns of vascular plants, mosses and testate amoebae along the bog-fen gradient reveal different responses of aboveground and belowground communities to ecological gradients

Edward Mitchell, Mariusz Lamentowicz

Vegetation responses to environmental gradients in peatlands are well documented but little is known about how these patterns compare with those of soil organisms. We studied the vegetation, testate amoebae, and abiotic variables (depth of the water table ...

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