Publications associées à Phosphorylation oxydative

Sample Enrichment for Bioanalytical Assessment of Disinfected Drinking Water: Concentrating the Polar, the Volatiles, and the Unknowns

Urs von Gunten

Enrichment methods used in sample preparation for the bioanalytical assessment of disinfected drinking water result in the loss of volatile and hydrophilic disinfection byproducts (DBPs) and hence likely tend to underestimate biological effects. We develop ...

American Chemical Society2016

Structure of fully protonated proteins by proton-detected magic-angle spinning NMR

David Lyndon Emsley, Andrea Bertarello

Protein structure determination by proton-detected magic-angle spinning (MAS) NMR has focused on highly deuterated samples, in which only a small number of protons are introduced and observation of signals from side chains is extremely limited. Here, we sh ...

National Academy of Sciences2016

Characterization of intracellular metabolic states in the origin of the metabolic reprogramming of cancer cells

Vassily Hatzimanikatis, Meriç Ataman, Joana Raquel Pinto Vieira

Cancer cells have been observed to undergo a metabolic reprogramming in which glycolytic fluxes are upregulated whereas oxidative phosphorylation is downregulated. This metabolic phenotype is known as the Warburg effect and it is observed even under high o ...

2015

Evidence for a Direct Effect of the NAD(+) Precursor Acipimox on Muscle Mitochondrial Function in Humans

Johan Auwerx, Evan Graehl Williams, Norman Lionel Moullan, Eija Riitta Pirinen

Recent preclinical studies showed the potential of nicotinamide adenine dinucleotide (NAD(+)) precursors to increase oxidative phosphorylation and improve metabolic health, but human data are lacking. We hypothesize that the nicotinic acid derivative acipi ...

American Diabetes Association2015

Portable oxidative stress sensor: Dynamic and non-invasive measurements of extracellular H2O2 released by algae

Olivier Martin, Christian Santschi, Volodymyr Koman

Reactive oxygen species (ROS) generated by aerobic organisms are essential for physiological processes such as cell signaling, apoptosis, immune defense and oxidative stress mechanisms. Unbalanced oxidant/antioxidant budgets are involved in many diseases a ...

Elsevier Advanced Technology2015

Pd/C-Catalyzed Cyclizative Cross-Coupling of Two ortho-Alkynylanilines under Aerobic Conditions: Synthesis of 2,3’-Bisindoles

Qian Wang, Jieping Zhu, Bo Yao

A palladium-catalyzed cyclizative cross-coupling of two o-alkynylanilines to 2,3’-bisindoles under aerobic oxidative conditions was developed. Mechanistic studies suggested that the two catalytic cycles, namely the formation of 3-alkynylindoles 8 and their ...

Wiley-Blackwell2015

Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo

Hilal Lashuel, Magdalena Zweckstetter, Abid Oueslati, Mohamed Bilal Fares, Martial Mbefo Kamdem

Although α-synuclein (α-syn) phosphorylation has been considered as a hallmark of sporadic and familial Parkinson disease (PD), little is known about the effect of PD-linked mutations on α-syn phosphorylation. In this study, we investigated the effects of ...

American Society for Biochemistry and Molecular Biology2015

Phosphorylation of the nuclear receptor co-repressor 1 by protein kinase B (PKB/Akt) switches its co-repressor targets in the liver

Johan Auwerx, Kristina Schoonjans, Dongryeol Ryu, Xu Wang, Adriano Maida

The nuclear receptor corepressor 1 (NCoR1) is a transcriptional co-regulator that has wide-ranging effects on gene expression patterns. In the liver, NCoR1 represses lipid synthesis in the fasting state, whereas it inhibits the activation of PPARα upon fee ...

Wiley-Blackwell2015

Dynamics of Interfacial Electron Transfer from Betanin to Nanocrystalline TiO2: The Pursuit of Two-Electron Injection

Jacques-Edouard Moser, Arianna Marchioro

We report spectroelectrochemical and transient absorption spectroscopic studies of electron injection from the plant pigment betanin (Bt) to nanocrystalline TiO2. Spectroelectrochemical experiments and density functional theory (DFT) calculations are used ...

American Chemical Society2015

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Phosphorylation oxydative

Sample Enrichment for Bioanalytical Assessment of Disinfected Drinking Water: Concentrating the Polar, the Volatiles, and the Unknowns

Structure of fully protonated proteins by proton-detected magic-angle spinning NMR

Characterization of intracellular metabolic states in the origin of the metabolic reprogramming of cancer cells

Evidence for a Direct Effect of the NAD(+) Precursor Acipimox on Muscle Mitochondrial Function in Humans

Portable oxidative stress sensor: Dynamic and non-invasive measurements of extracellular H2O2 released by algae

Pd/C-Catalyzed Cyclizative Cross-Coupling of Two ortho-Alkynylanilines under Aerobic Conditions: Synthesis of 2,3’-Bisindoles

Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo

Phosphorylation of the nuclear receptor co-repressor 1 by protein kinase B (PKB/Akt) switches its co-repressor targets in the liver

Dynamics of Interfacial Electron Transfer from Betanin to Nanocrystalline TiO2: The Pursuit of Two-Electron Injection

Dependence of Hippocampal Function on ERR gamma-Regulated Mitochondrial Metabolism

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Chattez avec Graph Search

Structure of fully protonated proteins by proton-detected magic-angle spinning NMR

Sample Enrichment for Bioanalytical Assessment of Disinfected Drinking Water: Concentrating the Polar, the Volatiles, and the Unknowns

Evidence for a Direct Effect of the NAD(+) Precursor Acipimox on Muscle Mitochondrial Function in Humans

Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo

Dependence of Hippocampal Function on ERR gamma-Regulated Mitochondrial Metabolism

Portable oxidative stress sensor: Dynamic and non-invasive measurements of extracellular H2O2 released by algae

Phosphorylation of the nuclear receptor co-repressor 1 by protein kinase B (PKB/Akt) switches its co-repressor targets in the liver

Dynamics of Interfacial Electron Transfer from Betanin to Nanocrystalline TiO2: The Pursuit of Two-Electron Injection

Characterization of intracellular metabolic states in the origin of the metabolic reprogramming of cancer cells

Pd/C-Catalyzed Cyclizative Cross-Coupling of Two ortho-Alkynylanilines under Aerobic Conditions: Synthesis of 2,3’-Bisindoles