Concept

Phényléthylamine

Publications associées (38)

Reactivity of Substituted Benzotrichlorides toward Granular Iron, Cr(II), and an Iron(II) Porphyrin: A Correlation Analysis

Abstract: Cross-correlations of rate constants between a system of interest and a better-defined one have become popular as a tool in studying transformations of organic pollutants. A slope of unity (if the correlation is conducted on a log-log basis) in s ...

American Chemical Society2006

Mutants of o6-alkylguanine-dna alkyltransferase

Kai Johnsson, Christian Heinis, Alexandre Juillerat, Christopher Chidley, Thomas Gronemeyer, Antje Keppler

The invention relates to AGT mutants showing, when compared to the wild type human AGT, two or more advantageous properties selected from (a) reduced DNA interaction (b) localisation of the expressed protein in eukaryotic cells that is no longer restricted ...

2006

Total asymmetric synthesis of (-)-conduramine B-1 and of its enantiomer. N-Benzyl derivatives of conduramine B-1 are beta-glucosidase inhibitors

Pierre Vogel

The 'naked sugars' (+)- and (-)-7-oxabicyclo[2.2.1]hept-5-en-2-one have been converted into (-)-conduramine B-1 ((-)3) and its enantiomer (+)-3, respectively. They have been condensed with a variety of aldehydes in the presence of NaBH(OAC)(3). The N-subst ...

2005

Mutants of human O6-alkylguanine-DNA alkyltransferase with improved properties

Kai Johnsson, Christian Heinis, Alexandre Juillerat, Christopher Chidley, Thomas Gronemeyer, Antje Keppler

The invention relates to human O6-alkylguanine-DNA alkyltransferase (hAGT) mutants showing, when compared to the wild type human AGT, two or more advantageous properties selected from (a) reduced DNA interaction; (b) localization of the expressed protein i ...

(EPFL Ecole Polytechnique Federale de Lausanne, Switz.).2005

Synthesis of N-substituted (3S,4S)- and (3R,4R)-pyrrolidine-3,4-diols: Search for new glycosidase inhibitors

Pierre Vogel

N-Substituted (3S,4S)- and (3R,4R)-pyrrolidine-3,4-diols 9 and 10, respectively, were derived from (+)-L- and (-)-D-tartaric acid, respectively. Compounds 9k, 91, and 9m with the N-substituents, BnNH(CH2)(2), 4-Phc(6)H(4)CH(2)NH(CH2)(2) and 4-ClC6H4CH2NH(C ...

2004

Exploring structural opportunities: The regioflexible substitution of 1,3-difluorobenzene

Christophe Heiss

To demonstrate the superiority of modern organometallic methods, the inexpensive starting material 1,3-difluorobenzene has been selectively converted into the three benzoic acids and all seven bromobenzoic acids contg. the two fluorine atoms in homovicinal ...

2003

Trifluoromethoxy Substituted Anilines: Metalation as the Key Step for Structural Elaboration

Trifluoromethoxy-substituted anilines undergo hydrogen/lithium permutation ("metalation") with optional site selectivity depending on the N-protective group employed. N-tert-Butoxycarbonyl-2- and -4-(trifluoromethoxy)aniline react with tert-BuLi at the n ...

2003

A SOFC, with a solid electrolyte layer and at least one anode layer constituting a stratified structure. The anode layer incorporates a twice substituted lanthanide chromite, substituted by Sr on A sites and by Ni or Cu on B sites. The stratified structure ...

2003

Synthesis of the C-disaccharide alpha-C(1 -> 3)-L-fucopyranoside of N-acetylgalactosamine

Pierre Vogel

Radical C-glycosidation of racemic 5-exo-benzeneselenyl-6-endo-chloro-3-methylidene-7-oxabicyclo[2.2.1]hept an-2-one ((+/-)-2) with alpha -acetobromofucose (3) provided a mixture of alpha -C-fucosides that were reduced with NaBH4 to give two diastereomeric ...

2001

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Brain glycogen levels are dynamically regulated by certain neurotransmitters, including noradrenaline (NA) and vasoactive intestinal peptide (VIP). In particular, glycogen synthesis involves activation by NA and VIP of the transcription factors C/EBPbeta a ...

Wiley-Blackwell2000

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