Concept

Motor system

Publications associées (116)

Parallel pathways from motor and somatosensory cortex for controlling whisker movements in mice

Mice can gather tactile sensory information by actively moving their whiskers to palpate objects in their immediate surroundings. Whisker sensory perception therefore requires integration of sensory and motor information, which occurs prominently in the ne ...

Wiley-Blackwell2015

Decoding bipedal locomotion from the rat sensorimotor cortex

Silvestro Micera, Grégoire Courtine, Rubia van den Brand, Jacopo Rigosa, Lucia Florinda Friedli Wittler

Objective. Decoding forelimb movements from the firing activity of cortical neurons has been interfaced with robotic and prosthetic systems to replace lost upper limb functions in humans. Despite the potential of this approach to improve locomotion and fac ...

Institute of Physics2015

Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush

Pierre Magistretti, Sylvain Eric Lengacher, Luc Pellerin, Lin Jin

Peripheral nerve regeneration following injury occurs spontaneously, but many of the processes require metabolic energy. The mechanism of energy supply to axons has not previously been determined. In the central nervous system, monocarboxylate transporter ...

Elsevier2015

Neuroprosthetic rehabilitation and translational mechanism after severe spinal cord injury

Lucia Florinda Friedli Wittler

Traumatic SCIs have long-term health, economic and social consequences, stressing the urgency to develop interventions to improve recovery after such injuries. Today, the only proven effective interventions to enhance recovery after SCI are activity-based ...

EPFL2014

Disrupting the ipsilateral motor cortex interferes with training of a complex motor task in older adults

Friedhelm Christoph Hummel

Performance of unimanual movements is associated with bihemispheric activity in the motor cortex in old adults. However, the causal functional role of the ipsilateral MC (iMC) for motor control is still not completely known. Here, the behavioral consequenc ...

Oxford University Press2014

Function Identification in Neuron Populations via Information Bottleneck

Michael Christoph Gastpar, Sreenivas Kartik Buddha

It is plausible to hypothesize that the spiking responses of certain neurons represent functions of the spiking signals of other neurons. A natural ensuing question concerns how to use experimental data to infer what kind of a function is being computed. M ...

MDPI AG2013

A Biophysically Detailed Model of Neocortical Local Field Potentials Predicts the Critical Role of Active Membrane Currents

Henry Markram, Sean Lewis Hill, Michael Reimann, Rodrigo de Campos Perin

Brain activity generates extracellular voltage fluctuations recorded as local field potentials (LFPs). It is known that the relevant microvariables, the ionic currents across membranes, jointly generate the macrovariables, the extracellular voltage, but ne ...

Elsevier2013

Acquired control of ventral premotor cortex activity by feedback training: an exploratory real-time FMRI and TMS study

Friedhelm Christoph Hummel

Despite the availability of various options for movement restoration in stroke patients, there is no effective treatment for patients who show little or no functional recovery of upper limb motor function. ...

2012

Redundant information encoding in primary motor cortex during natural and prosthetic motor control

Michael Christoph Gastpar

Redundant encoding of information facilitates reliable distributed information processing. To explore this hypothesis in the motor system, we applied concepts from information theory to quantify the redundancy of movement-related information encoded in the ...

Springer Verlag2012

Continuous decoding of grasping tasks for a prospective implantable cortical neuroprosthesi

Silvestro Micera

Background: In the recent past several invasive cortical neuroprostheses have been developed. Signals recorded from the motor cortex (area MI) have been decoded and used to control computer cursors and robotic devices. Nevertheless, few attempts have been ...

BioMed Central2012

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