Concept

Valve cardiaque

Publications associées (81)

Isogeometric Analysis of Electrophysiological Models on Surfaces

In this project we numerically simulate electrophysiological models for cardiac applications by means of Isogeometric Analysis. Specifically, we aim at understanding the advantages of using high order continuous NURBS (Non-UniformRational B-Splines) basis ...

2014

Manipulating flow separation: sensitivity of stagnation points, separatrix angles and recirculation area to steady actuation

François Gallaire, Edouard Boujo

A variational technique is used to derive analytical expressions for the sensitivity of several topological indicators of flow separation to steady actuation. Considering the boundary layer flow above a wall-mounted bump, the six following representative q ...

Royal Soc2014

Novel non-invasive techniques for hemodynamic monitoring

Orestis Vardoulis

The monitoring of hemodynamic parameters is crucial for optimal patient management and treatment. However, established methods are often invasive and possibly inapplicable to sensitive age groups. Novel, non-invasive techniques have the potential to transf ...

EPFL2014

Helical flows and asymmetry of blood jet in dilated ascending aorta with normally functioning bicuspid valve

Alfio Quarteroni, Christian Vergara, Elena Faggiano

Bicuspid aortic valve (BAV) is associated with aortic dilatation and aneurysm. Several studies evidenced an eccentric systolic flow in ascending aorta associated with increased wall shear stresses (WSS) and the occurrence of an helical systolic flow. This ...

Springer Heidelberg2013

Reduced order models for the simulation of pathological heart valves

Lidia Stepanova

Numerical modeling of the human cardiovascular system (CVS) represents an active branch of research which allows the medical specialists to advance in understanding of underlined processes of blood circulation and the heart work at any scale, moreover, it ...

2013

Comprehensive analysis of Lenz effect on the artificial heart valves during magnetic resonance imaging

Juan Ramon Mosig, Laleh Golestanirad

This work presents results of a comprehensive analysis of the Lenz effect due to motion of artificial heart valves during magnetic resonance imaging. The interaction of rotating metallic heart valves with magnetic fields is studied by performing a time-dom ...

2012

Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome

Freddy Radtke

The Notch signaling pathway is an important contributor to the development and homeostasis of the cardiovascular system. Not surprisingly, mutations in Notch receptors and ligands have been linked to a variety of hereditary diseases that impact both the he ...

Company of Biologists2012

An extracellular matrix protein microarray to study endothelial to mesenchymal transformation in mitral valve endothelial cells

Blaise Calpe

In the developing heart, a subset of endothelial cells (ECs) undergo a process of endothelial to mesenchymal transformation (EMT) that leads to the remodeling of the cardiac cushions and the formation of the cardiac valves. Understanding how microenvironme ...

2011

Geometrical multiscale model of an idealized left ventricle with fluid-structure interaction effects coupled to a one-dimensional viscoelastic arterial network

Simone Deparis, Toni Mikael Lassila, Adelmo Cristiano Innocenza Malossi

A geometrical multiscale model for blood flow through an ideal left ventricle and the main arteries is presented. The blood flow in the three-dimensional idealized left ventricle is solved through a monolithic fluid-structure interaction solver. To account ...

2011

Tracking of Stepwise Ablation of Persistent Atrial Fibrillation using Synchronization of nearby Electrograms

Jean-Marc Vesin, Andréa Buttu, Etienne Pruvot, Sarah Volorio

Purpose: The timing of bipolar intracardiac electrograms (EGMs) during atrial fibrillation (AF) reflects the dynamics of AF wavelets. The extent of synchronization between EGMs is an indirect measure of AF spatial organization. Our study intends to determi ...

Ieee2011

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