Estrogen (medication)An estrogen (E) is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy, and as part of feminizing hormone therapy for transgender women. They can also be used in the treatment of hormone-sensitive cancers like breast cancer and prostate cancer and for various other indications. Estrogens are used alone or in combination with progestogens. They are available in a wide variety of formulations and for use by many different routes of administration.
Premarin (médicament)Le Premarin est un médicament à base d'œstrogènes conjugués, utilisé pour traiter les troubles de la ménopause chez la femme. Son nom vient de l'anglais pregnant mare urine désignant l'ingrédient principal, l'urine de jument gestante. Il a été mis sur le marché pour la première fois par l’entreprise Pfizer en 1941. D'autres médicaments utilisent des œstrogènes conjugués d'origine équine, comme le Premplus, commercialisé par le même entreprise, le Climopax et le Duavive.
Progesterone (medication)Progesterone (P4) is a medication and naturally occurring steroid hormone. It is a progestogen and is used in combination with estrogens mainly in hormone therapy for menopausal symptoms and low sex hormone levels in women. It is also used in women to support pregnancy and fertility and to treat gynecological disorders. Progesterone can be taken by mouth, vaginally, and by injection into muscle or fat, among other routes. A progesterone vaginal ring and progesterone intrauterine device used for birth control also exist in some areas of the world.
Steroidal antiandrogenA steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure. They are typically antagonists of the androgen receptor (AR) and act both by blocking the effects of androgens like testosterone and dihydrotestosterone (DHT) and by suppressing gonadal androgen production. SAAs lower concentrations of testosterone through simulation of the negative feedback inhibition of the hypothalamus. SAAs are used in the treatment of androgen-dependent conditions in men and women, and are also used in veterinary medicine for the same purpose.
Megestrol acetateMegestrol acetate (MGA), sold under the brand name Megace among others, is a progestin medication which is used mainly as an appetite stimulant to treat wasting syndromes such as cachexia. It is also used to treat breast cancer and endometrial cancer, and has been used in birth control. MGA is generally formulated alone, although it has been combined with estrogens in birth control formulations. It is usually taken by mouth.
Acétate de médroxyprogestéroneL’acétate de médroxyprogestérone (en anglais Medroxyprogesterone acetate ou MPA), connu aussi sous le nom acétate de 17α-hydroxy-6α-méthylprogestérone, ou Depo-Provera est une forme synthétique de progestérone. Il est utilisé principalement comme contraceptif mais sert aussi pour le traitement de l'endométriose. Ses actions pharmacologiques sur le système endocrinien sont : L'inhibition des gonadotrophines hypophysaires : hormone folliculostimulante (FSH) et hormone lutéinisante (LH).
Anti-androgèneLes anti-androgènes sont des molécules diminuant l'activité des hormones androgènes. Ils bloquent les récepteurs aux androgènes ou diminuant la synthèse des androgènes. Chez l'homme, ils sont utilisés dans le traitement de certains cancers de la prostate ou lorsqu'on a recours à une castration chimique. Chez la femme, ils sont utilisés dans les situations d'hyperandrogénie ou comme traitement de la transidentité par thérapie de remplacement d'hormone et dans certains cas pour traiter l'acné et l'hirsutisme.
Progestogen (medication)A progestogen, also referred to as a progestagen, gestagen, or gestogen, is a type of medication which produces effects similar to those of the natural female sex hormone progesterone in the body. A progestin is a synthetic progestogen. Progestogens are used most commonly in hormonal birth control and menopausal hormone therapy. They can also be used in the treatment of gynecological conditions, to support fertility and pregnancy, to lower sex hormone levels for various purposes, and for other indications.
