Concept
Gangrène
Publications associées (13)
Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene
Clostridium perfringens phospholipase C (PLC), also called alpha-toxin, is the major virulence factor in the pathogenesis of gas gangrene. The toxic activities of genetically engineered alpha-toxin variants harboring single amino-acid substitutions in thre ...
2000Genomic diversity and organization of virulence genes in the pathogenic anaerobe Clostridium perfringens
Pulsed-field gel electrophoresis has been used to assess genomic diversity and to identify virulence regions in 10 strains, representing all five serotypes, of the anaerobic pathogen Clostridium perfringens. Detailed physical and gene maps of the approxima ...
1992Molecular genetics and pathogenesis of Clostridium perfringens
Clostridium perfringens is the causative agent of a number of human diseases, such as gas gangrene and food poisoning, and many diseases of animals. Recently significant advances have been made in the development of C. perfringens genetics. Studies on bact ...
1991