Concept

Consolidation osseuse

Publications associées (145)

Peri-implant bone remodeling after total hip replacement combined with systemic alendronate treatment: a finite element analysis

Dominique Pioletti, Lalaonirina Rakotomanana Ravelonarivo, Bastian Peter

In order to decrease the peri-implant bone loss during the life-time of the implant, oral use of anti-osteoporosis drugs (like bisphosphonates) has been suggested. In this study, bone remodeling parameters identified from clinical trials of alendronate wer ...

2004

High-resolution AFM imaging of intact and fractured trabecular bone

Georg Fantner

Nanoscale structural analyses of biomineralized materials can frequently help elucidate important structure-function relationships in these complex organic-inorganic composites. Atomic force microscope (AFM) imaging of the exterior surface of trabecular bo ...

2004

Influence of the degradation of the organic matrix on the microscopic fracture behavior of trabecular bone

Georg Fantner

In recent years, the important role of the organic matrix for the mechanical properties of bone has become increasingly apparent. It is therefore of great interest to understand the interactions between the organic and inorganic constituents of bone and le ...

2004

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation

Boris Hinz, Philippe Bugnon

An increasing number of patients are being treated with growth hormone (GH) for the enhancement of body growth but also as an anti-aging strategy. However, the side effects of GH have been poorly defined. In this study we determined the effect of GH on wou ...

American Society for Biochemistry and Molecular Biology2004

Leptin: cutting the fat off the bone

Johan Auwerx

CONTEXT: Leptin was initially proposed to be the antiobesity hormone. Now it is realised that leptin is more a signal molecule that communicates nutritional status to the brain, and that it is involved in bone formation by having an antiosteogenic action. ...

2003

Injectable calcium phosphate hydraulic cement (CPHC) used for periodontal tissue regeneration: A study of a dog model

Jacques Lemaître, Pascale Van Landuyt

Injectable calcium phosphate hydraulic cement (CPHC) is a new bone substitute family. This study aimed to evaluate the use of CPHC in surgical periodontitis-simulating defects in a dog model. CPHC was obtained by adding powder mixtures of different calcium ...

2003

Repair of bone defects using synthetic mimetics of collagenous extracellular matrices

Matthias Lütolf, Jeffrey Alan Hubbell, Randoald Müller

We have engineered synthetic poly(ethylene glycol) (PEG)-based hydrogels as cell-ingrowth matrices for in situ bone regeneration. These networks contain a combination of pendant oligopeptide ligands for cell adhesion (RGDSP) and substrates for matrix metal ...

2003

Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: Engineering cell-invasion characteristics

Matthias Lütolf, Jeffrey Alan Hubbell

Synthetic hydrogels have been molecularly engineered to mimic the invasive characteristics of native provisional extracellular matrixes: a combination of integrin-binding sites and substrates for matrix metalloproteinases (MMP) was required to render the n ...

2003

Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles

Dominique Pioletti

Particles generated from orthopedic implants through years of wear play an essential role in the aseptic loosening of a prosthesis. We have investigated the biocompatibility of these orthopedic particles on different osteoblast-like cells representative of ...

2002

Active biocoating for bone implant

Dominique Pioletti, Lalaonirina Rakotomanana Ravelonarivo

This invention relates to a bone implant coated with a layer which releases an active agent in order to control the bone remodeling. ...

2002

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search