Publications associées à Séquence régulatrice

The genome of Dehalobacter restrictus - high gene redundancy for a restricted metabolism

Christof Holliger, Julien Maillard, Aamani Rupakula Boyanapalli, Hauke Smidt

Organohalide respiration (OHR) is a bacterial anaerobic respiratory metabolism dedicated to use halogenated compounds as terminal electron acceptors. OHR bacteria are strictly anaerobic microorganisms which use reductive dehalogenases (RdhA) as key enzymes ...

2012

Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility

Alexandre Gattiker

Mammalian spermatogenesis is a process that involves a complex expression program in both somatic and germ cells present in the male gonad. A number of studies have attempted to define the transcriptome of male meiosis and gametogenesis in rodents and prim ...

Oxford University Press2012

Genomic context analysis reveals dense interaction network between vertebrate ultraconserved non-coding elements

Philipp Bucher, Slavica Dimitrieva Janeva

Motivation: Genomic context analysis, also known as phylogenetic profiling, is widely used to infer functional interactions between proteins but rarely applied to non-coding cis-regulatory DNA elements. We were wondering whether this approach could provide ...

Oxford University Press2012

Topology and Dynamics of the Zebrafish Segmentation Clock Core Circuit

Bart Deplancke, Andrew Charles Oates, Sebastian Maerkl, Daniele Soroldoni, Alina Isakova

During vertebrate embryogenesis, the rhythmic and sequential segmentation of the body axis is regulated by an oscillating genetic network termed the segmentation clock. We describe a new dynamic model for the core pace-making circuit of the zebrafish segme ...

Public Library Science2012

Topology and dynamics of the zebrafish segmentation clock core circuit

Bart Deplancke, Andrew Charles Oates, Sebastian Maerkl, Daniele Soroldoni, Alina Isakova

2012

The corrinoid metabolism in desulfitobacterium hafniense - genetic and regulatory aspects

Christof Holliger, Julien Maillard, Emmanuelle Rohrbach, Aurélie Duret

Corrinoids (e.g. vitamin B12, cobalamin) represent a family of complex organometallic cofactors essential to the metabolism of microorganisms, animal and humans, and are involved in several enzymes such as isomerases, methyltransferases and reductive dehal ...

2012

RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal that PTF1a Stabilizes Pancreas Progenitor Identity via the Control of MNX1/HLXB9 and a Network of Other Transcription Factors

Emilie Gesina, Philipp Bucher, Anne Grapin-Botton, Nancy Thompson

Pancreas development is initiated by the specification and expansion of a small group of endodermal cells. Several transcription factors are crucial for progenitor maintenance and expansion, but their interactions and the downstream targets mediating their ...

American Society for Microbiology2012

Regulatory T-Cells and Associated Pathways in Metastatic Renal Cell Carcinoma (mRCC) Patients Undergoing DC-Vaccination and Cytokine-Therapy

Benita Wolf

To evaluate CD4(+)CD25(+)FOXP3(+) T regulatory cells (T(REG)) and associated immune-regulatory pathways in peripheral blood lymphocytes (PBL) of metastatic renal cell carcinoma (mRCC) patients and healthy volunteers. We subsequently investigated the effect ...

Public Library of Science2012

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Séquence régulatrice

The genome of Dehalobacter restrictus - high gene redundancy for a restricted metabolism

Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility

Genomic context analysis reveals dense interaction network between vertebrate ultraconserved non-coding elements

Reverse Engineering and Analysis of Genome-Wide Gene Regulatory Networks from Gene Expression Profiles Using High-Performance Computing

Topology and Dynamics of the Zebrafish Segmentation Clock Core Circuit

Topology and dynamics of the zebrafish segmentation clock core circuit

The corrinoid metabolism in desulfitobacterium hafniense - genetic and regulatory aspects

RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal that PTF1a Stabilizes Pancreas Progenitor Identity via the Control of MNX1/HLXB9 and a Network of Other Transcription Factors

The transcriptional landscape of hematopoietic stem cell ontogeny

Regulatory T-Cells and Associated Pathways in Metastatic Renal Cell Carcinoma (mRCC) Patients Undergoing DC-Vaccination and Cytokine-Therapy

Graph Chatbot

Chattez avec Graph Search

Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility

Genomic context analysis reveals dense interaction network between vertebrate ultraconserved non-coding elements

Reverse Engineering and Analysis of Genome-Wide Gene Regulatory Networks from Gene Expression Profiles Using High-Performance Computing

Topology and Dynamics of the Zebrafish Segmentation Clock Core Circuit

The genome of Dehalobacter restrictus - high gene redundancy for a restricted metabolism

Regulatory T-Cells and Associated Pathways in Metastatic Renal Cell Carcinoma (mRCC) Patients Undergoing DC-Vaccination and Cytokine-Therapy

Topology and dynamics of the zebrafish segmentation clock core circuit

RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal that PTF1a Stabilizes Pancreas Progenitor Identity via the Control of MNX1/HLXB9 and a Network of Other Transcription Factors

The corrinoid metabolism in desulfitobacterium hafniense - genetic and regulatory aspects

The transcriptional landscape of hematopoietic stem cell ontogeny