Concept

Clairance (biologie)

Publications associées (22)

The interplay between white adipose tissue, adipokines, and structural gray matter changes

Jean-Philippe Thiran, Gabriel Girard, Elda Fischi Gomez, Liana Okudzhava

The growing global obesity issue emphasizes the importance of understanding its health implications. Previous research has identified consistent alterations in gray matter (GM) volume in connection with obesity. Given the various implications of distinct f ...

Wiley2024

Early Urinary Biomarkers in Pediatric Autosomal Dominant Polycystic Kidney Disease (ADPKD): No Evidence in the Interest of Urinary Neutrophil Gelatinase-Associated Lipocalin (uNGAL)

Marco Solcà

Background: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is increasingly diagnosed during childhood by the presence of renal cysts in patients with a positive familial history. No curative treatment is available and early detection and diagnosis co ...

FRONTIERS MEDIA SA2019

Observation of enhanced ion particle transport in mixed H/D isotope plasmas on JET

Olivier Sauter, Ambrogio Fasoli, Basil Duval, Stefano Coda, Jonathan Graves, Yves Martin, Duccio Testa, Patrick Blanchard, Alessandro Pau, Cristian Sommariva, Michele Marin, Henri Weisen, Richard Pitts, Yann Camenen, Jan Horacek, Javier García Hernández, Marco Wischmeier, Nicola Vianello, Mikhail Maslov, Federico Nespoli, Yao Zhou, David Pfefferlé, Davide Galassi, Antonio José Pereira de Figueiredo, Jonathan Marc Philippe Faustin, Liang Yao, Dalziel Joseph Wilson, Hamish William Patten, Samuel Lanthaler, Bernhard Sieglin, Otto Asunta

Particle transport in tokamak plasmas has been intensively studied in the past, particularly in relation to density peaking and the presence of anomalous inward particle convection in L-and H-modes. While in the L-mode case the presence of the anomalous in ...

2018

Controlling and Monitoring Intracellular Delivery of Anticancer Polymer Nanomedicines

Harm-Anton Klok, Claudia Battistella

Polymer nanomedicines are very attractive to improve the delivery of chemotherapeutics. Polymer conjugates and other polymer-based nanocarriers allow to increase plasma half-life and drug bioavailability and can also be guided toward tumors using passive a ...

2017

Development of an albumin-binding ligand for prolonging the plasma half-life of peptide therapeutics

Alessandro Zorzi

Peptides represent a promising format for the development of therapeutics since they combine the advantages of proteins and small molecules. Several techniques based on rational design or in vitro evolution can be used to develop peptides as therapeutics. ...

EPFL2017

High-beta, steady-state hybrid scenario on DIII-D

Holger Reimerdes

The potential of the hybrid scenario (first developed as an advanced inductive scenario for high fluence) as a regime for high-beta, steady-state plasmas is demonstrated on the DIII-D tokamak. These experiments show that the beneficial characteristics of h ...

Iop Publishing Ltd2016

Novel aspects of plasma control in ITER

Olivier Sauter, Federico Alberto Alfredo Felici, Jonathan Bryan Lister, Sun Hee Kim

ITER plasma control design solutions and performance requirements are strongly driven by its nuclear mission, aggressive commissioning constraints, and limited number of operational discharges. In addition, high plasma energy content, heat fluxes, neutron ...

Amer Inst Physics2015

Development of real-time plasma analysis and control algorithms for the TCV tokamak using SIMULINK

Olivier Sauter, Basil Duval, Stefano Coda, Timothy Goodman, Jean-Marc Moret, Federico Alberto Alfredo Felici, Alexander Karpushov, Wouter Vijvers, Alessandro Bortolon, James Paley, Lucia Isabel Federspiel, Francesco Piras, Hoang Bao Le, Andreas Pitzschke

One of the key features of the new digital plasma control system installed on the TCV tokamak is the possibility to rapidly design, test and deploy real-time algorithms. With this flexibility the new control system has been used for a large number of new e ...

Elsevier Science Sa2014

Measured and Modeled Toxicokinetics in Cultured Fish Cells and Application to In Vitro - In Vivo Toxicity Extrapolation

Kristin Schirmer, Julita Maria Stadnicka-Michalak

Effect concentrations in the toxicity assessment of chemicals with fish and fish cells are generally based on external exposure concentrations. External concentrations as dose metrics, may, however, hamper interpretation and extrapolation of toxicological ...

Public Library Science2014

Development of real-time plasma analysis and control algorithms for the TCV tokamak using SIMULINK

Olivier Sauter, Basil Duval, Stefano Coda, Timothy Goodman, Jean-Marc Moret, Federico Alberto Alfredo Felici, Wouter Vijvers, Alessandro Bortolon, James Paley, Lucia Isabel Federspiel, Francesco Piras, Hoang Bao Le, Andreas Pitzschke

Elsevier2013

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