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On-chip cell handling and analysis is given more and more interest, as new cytometry devices can be realised or efficiently combined and integrated. The developed sensor presents several improvements compared to other integrated flow cytometers. It is aime ...
The CD28 ligands CD80 and CD86 are expressed on APC, and both provide costimulatory function. However, the reason for the expression of two separate CD28 ligands remains unclear. We have previously shown that blockade of CD80 costimulation by Y100F-Ig, a C ...
A new cytological tool, based on the micro Coulter particle counter (CPC) principle, aimed at diagnostic applications for cell counting and separation in haematology, oncology or toxicology is described. The device measures the spectral impedance of indivi ...
We investigate a one-dimensional model of blood flow in human arteries. In particular, we consider the case when an abrupt variation of mechanical characteristic of artery is caused by the presence of a vascular prosthesis. The derivations of the model and ...
The low frequency of precursor cells specific for any particular antigen (Ag) makes it difficult to characterize preimmune T cell receptor (TCR) repertoires and to understand repertoire selection during an immune response. We have undertaken a combined ado ...
Replacement of the hyperimmune anti-Rhesus (Rh) D immunoglobulin, currently used to prevent haemolytic disease of the newborn, by fully recombinant human anti-RhD antibodies would solve the current logistic problems associated with supply and demand. The c ...
The design, fabrication techniques and characterization of an on-chip flow- cytometer device as well as the packaging approach is described. The device consists of planar microelectrodes situated on one or both sides of a micro- channel connected to an ele ...
A family of graft copolymers that can sterically inhibit interactions between biological surfaces was developed. These copolymers contained phenylboronic acid (PBA) groups as saccharide-binding moieties on a poly-(L-lysine) backbone and poly(ethylene glyco ...
Although Drosophila possesses potent immune responses, little is known about the microbial pathogens that infect Drosophila. We have identified members of the bacterial genus Erwinia that induce the systemic expression of genes encoding antimicrobial pepti ...
In this note, we consider some issues relevant for the application of Computational Fluid Dynamics to biomedical vascular investigations. More precisely, models for blood and vessel walls are briefly addressed together with some preliminary results in the ...