Concept

Pandémie

Publications associées (64)

Frequentist estimation of an epidemic's spreading potential when observations are scarce

We consider the problem of inferring the potential of an epidemic for escalating into a pandemic on the basis of limited observations in its initial stages. Classical results of Becker & Hasofer (J. R. Statist. Soc. B, 59, 415-29) illustrate that frequenti ...

Oxford University Press2014

Hydrological, Anthropogenic and Ecological Processes in Cholera Dynamics

Lorenzo Righetto

The present Thesis deals with understanding, measuring and modelling epidemic cholera. The relevance of the endeavour stems from the fact that mathematical epidemiology, properly guided by model-guided field validation, is a reliable and powerful tool to m ...

EPFL2013

Drug-resistant tuberculosis: time for visionary political leadership

Stewart Cole

Two decades ago, WHO declared tuberculosis a global emergency, and invested in the highly cost-effective directly observed treatment short-course programme to control the epidemic. At that time, most strains of Mycobacterium tuberculosis were susceptible t ...

Elsevier2013

Reassessment of the 2010-2011 Haiti cholera outbreak and rainfall-driven multiseason projections

Andrea Rinaldo, Melanie Blokesch, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto, Marino Gatto

Mathematical models can provide key insights into the course of an ongoing epidemic, potentially aiding real-time emergency management in allocating health care resources and by anticipating the impact of alternative interventions. We study the ex post rel ...

2012

Modelling cholera epidemics: the role of waterways, human mobility and sanitation

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto, Marino Gatto

We investigate the role of human mobility as a driver for long-range spreading of cholera infections, which primarily propagate through hydrologically controlled ecological corridors. Our aim is to build a spatially explicit model of a disease epidemic, wh ...

2012

Removal of the antiviral agent oseltamivir and its biological activity by oxidative processes

Urs von Gunten, Kristin Schirmer, Silvio Canonica

The antiviral agent oseltamivir acid (OA, the active metabolite of Tamiflu) may occur at high concentrations in wastewater during pandemic influenza events. To eliminate OA and its antiviral activity from wastewater, ozonation and advanced oxidation proces ...

2012

A high-resolution human contact network for infectious disease transmission

Marcel Salathé

The most frequent infectious diseases in humans--and those with the highest potential for rapid pandemic spread--are usually transmitted via droplets during close proximity interactions (CPIs). Despite the importance of this transmission route, very little ...

2010

Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm

Stewart Cole, Iain Old

BACKGROUND: A resequencing microarray called PathogenID v2.0 has been developed and used to explore various strategies of sequence selection for its design. The part dedicated to influenza viruses was based on consensus sequences specific for one gene gene ...

BioMed Central2010

An Optofluidic Nanoplasmonic Biosensor for Direct Detection of Live Viruses from Biological Media

Hatice Altug, Min Huang

Fast and sensitive virus detection techniques which can be rapidly deployed at multiple sites are essential to prevent and control future epidemics and bioterrorism threats In this Letter we demonstrate a label free optofluidic nanoplasmonic sensor that ca ...

2010

How Efficient Can Gossip Be? (On the Cost of Resilient Information Exchange)

Rachid Guerraoui, Seth Gilbert, Dan Alistarh, Morteza Zadimoghaddam

Gossip, also known as epidemic dissemination, is becoming an in- creasingly popular technique in distributed systems. Yet, it has remained a partially open question: how robust are such protocols? We consider a natural ex- tension of the random phone-call ...

Springer2010

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