Concept
Electrophysiology study
Publications associées (37)
An integrated heart-torso electromechanical model for the simulation of electrophysiological outputs accounting for myocardial deformation
Alfio Quarteroni, Francesco Regazzoni
When generating in-silico clinical electrophysiological outputs, such as electrocardiograms (ECGs) and body surface potential maps (BSPMs), mathematical models have relied on single physics, i.e. of the cardiac electrophysiology (EP), neglecting the role o ...
Elsevier Science Sa2024Who says you are so sick? An investigation on individual susceptibility to cybersickness triggers using EEG, EGG and ECG
In this research paper, we conducted a study to investigate the connection between three objective measures: Electrocardiogram(ECG), Electrogastrogram (EGG), and Electroencephalogram (EEG), and individuals' susceptibility to cybersickness. Our primary obje ...
2024A single-beat algorithm to discriminate farfield from nearfield bipolar voltage electrograms from the pulmonary veins
Jean-Marc Vesin, Adrian Luca, Vincent Schlageter
Background Superimposition of farfield (FF) and nearfield (NF) bipolar voltage electrograms (BVE) complicates the confirmation of pulmonary vein (PV) isolation after catheter ablation of atrial fibrillation. Our aim was to develop an automatic algorithm ba ...
SPRINGER2023Cardiovascular response to closed-loop intraneural stimulation of the right vagus nerve: a proof-of-concept study
Vagus nerve stimulation (VNS) is an FDA-approved technique for the neuromodulation of the autonomic nervous system. There are many therapeutic applications where VNS could be used as a therapy, such as cardiovascular diseases, epilepsy, depression, and inf ...
New York2023PDE-Aware Deep Learning for Inverse Problems in Cardiac Electrophysiology
Alfio Quarteroni, Simone Deparis, Riccardo Tenderini, Stefano Pagani
In this work, we present a PDE-aware deep learning model for the numerical solution to the inverse problem of electrocardiography. The model both leverages data availability and exploits the knowledge of a physically based mathematical model, expressed by ...
2022Altered heart cytokine profile and action potential modulation in cardiomyocytes from Mas-deficient mice
The renin-angiotensin system (RAS) is a key hormonal system. In recent years, the functional analysis of the novel axis of the RAS (ACE2/Ang-(1-7)/Mas receptor) revealed that its activation can become pro-tective against several pathologies, including card ...
ACADEMIC PRESS INC ELSEVIER SCIENCE2022POD-Enhanced Deep Learning-Based Reduced Order Models for the Real-Time Simulation of Cardiac Electrophysiology in the Left Atrium
Alfio Quarteroni, Andrea Manzoni
The numerical simulation of multiple scenarios easily becomes computationally prohibitive for cardiac electrophysiology (EP) problems if relying on usual high-fidelity, full order models (FOMs). Likewise, the use of traditional reduced order models (ROMs) ...
FRONTIERS MEDIA SA2021A Computational Study of the Electrophysiological Substrate in Patients Suffering From Atrial Fibrillation
Alfio Quarteroni, Andrea Manzoni
In the context of cardiac electrophysiology, we propose a novel computational approach to highlight and explain the long-debated mechanisms behind atrial fibrillation (AF) and to reliably numerically predict its induction and sustainment. A key role is pla ...
FRONTIERS MEDIA SA2021