Concept
Minocycline
Publications associées (18)
Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction
Camille Véronique Bernadette Goemans, Christian Eugen Zimmerli, Martin Beck
Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative b ...
2024Early Neuroprotective Effects of Bovine Lactoferrin Associated with Hypothermia after Neonatal Brain Hypoxia-Ischemia in Rats
Neonatal hypoxic-ischemic (HI) encephalopathy (HIE) in term newborns is a leading cause of mortality and chronic disability. Hypothermia (HT) is the only clinically available therapeutic intervention; however, its neuroprotective effects are limited. Lacto ...
Basel2023Long-term imaging, automated high-content phenotyping and sorting of C. elegans larvae and embryos using microfluidic platforms
C. elegans is frequently studied to address fundamental biological questions motivated by its short life cycle, small size, hermaphrodite behavior and well-annotated genome. In this work, we present novel microfluidic platforms that support long-term cultu ...
EPFL2019Microfluidic high-content phenotypic screening on a Caenorhabditis elegans model
Caenorhabditis elegans is a performant model system for studying human biological processes and diseases and for pre-clinical phenotyping screenings of compounds. Microfluidics has been instrumental in enabling C. elegans-based drug assays, facilitating th ...
EPFL2018A design of experiment approach for efficient multi-parametric drug testing using a Caenorhabditis elegans model
Martinus Gijs, Matteo Cornaglia, Raphaël Etienne Jean Trouillon, Maria Cristina Letizia, Giuseppe Tranchida
When studying the drug effectiveness towards a target model, one should distinguish the effects of the drug itself and of all the other factors that could influence the screening outcome. This comprehensive knowledge is crucial, especially when model organ ...
2018Dynamics of antibiotics concentrations in the environment at different time scales
David Andrew Barry, Luca Rossi, Sylvain Coutu, Vera Wyrsch
The aim of this study was to assess the most relevant time scales of antibiotics concentration variations at the sewage treatment plant (STP) inlet and to create a model for the simulation of short-term concentration variations. During one year six antibio ...
2012