Publications associées à Immunosuppresseur

Yeast Three-Hybrid Screening for Identifying Anti-Tuberculosis Drug Targets

Mycobacterium goes yeast: Target deconvolution of anti-tuberculosis drugs can be a very challenging task. Here we report a yeast 3-hybrid system that allows promising small molecules to be screened for protein targets of a pathogen in nontoxic yeast cells. ...

Wiley-V C H Verlag Gmbh2013

Plug and Play Distributed Model Predictive Control Based on Distributed Invariance and Optimization

Colin Neil Jones, Giancarlo Ferrari Trecate, Ye Pu

This paper presents a method for plug-and-play distributed MPC of a network of interacting linear systems. The previously introduced idea of plug and play control addresses the challenge of performing network changes in the form of subsystems that are join ...

2013

Reduction-Sensitive Tioguanine Prodrug Micelles

Jeffrey Alan Hubbell, Urara Hasegawa

Colloidal drug and prodrug conjugates have unique targeting characteristics for tumor vasculature from the blood and for the lymphatics draining a tissue injection site. Tioguanine and tioguanine-generating prodrugs have been investigated as anticancer and ...

Amer Chemical Soc2012

Characterization of New Potential Anticancer Drugs Designed To Overcome Glutathione Transferase Mediated Resistance

Paul Joseph Dyson, Wee Han Ang, Jie Zhang

Resistance against anticancer drugs remains a serious obstacle in cancer treatment. Here we used novel strategies to target microsomal glutathione transferase 1 (MGST1) and glutathione transferase pi (GSTP) that are often overexpressed in tumors and confer ...

2011

Co-Pathological Connected Primary Neurons in a Microfluidic Device for Alzheimer Studies

Philippe Renaud, Robert Meissner, Anja Kunze, Serena Brando

This communication presents a novel experi- mental model for Alzheimer studies, where connected pri- mary neurons were set into subtend, co-pathological states. Cortical neurons were cultured in two separated cell com- partments in a microfluidic device. A ...

Wiley-Blackwell2011

Controlled release nanoparticle-embedded coatings reduce the tissue reaction to neuroprostheses

Philippe Renaud, André Mercanzini, Philippe Colin, Jeffrey Alan Hubbell, Jean-Charles Bensadoun, Sai Reddy

Controlled release coatings were developed for neuroprostheses with the aim of combating the tissue reaction following implantation in the brain. The coatings consist of poly(propylene sulfide) drug-eluting nanoparticles embedded in a poly(ethylene oxide) ...

Elsevier2010

Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis

Stewart Cole, Florence Pojer, Jeffrey Chen, Benjamin Blasco

Mycobacterium tuberculosis (M. tb) the causative agent of tuberculosis (TB) causes 1.7 million deaths annually. According to the World Health Organization, in some areas of the world, 25% of TB cases are due to multi- or extensively drug resistant M. tb st ...

Elsevier2010

Extracellular matrix binding mixed micelles for drug delivery applications

Davide Demurtas, Jeffrey Alan Hubbell, Jutta Christine Wandrey

Received 5 January 2009 Accepted 22 March 2009 Available online 27 March 2009 Keywords: Mixed micelles Drug delivery Block copolymers Sirolimus Extracellular matrix We present the formation of collagen-binding mixed micelles and their potential suitability ...

2009

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Immunosuppresseur

Yeast Three-Hybrid Screening for Identifying Anti-Tuberculosis Drug Targets

Plug and Play Distributed Model Predictive Control Based on Distributed Invariance and Optimization

Reduction-Sensitive Tioguanine Prodrug Micelles

Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion

Characterization of New Potential Anticancer Drugs Designed To Overcome Glutathione Transferase Mediated Resistance

Co-Pathological Connected Primary Neurons in a Microfluidic Device for Alzheimer Studies

Polylactide-cyclosporin A nanoparticles for targeted immunosuppression

Controlled release nanoparticle-embedded coatings reduce the tissue reaction to neuroprostheses

Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis

Extracellular matrix binding mixed micelles for drug delivery applications

Graph Chatbot

Chattez avec Graph Search

Yeast Three-Hybrid Screening for Identifying Anti-Tuberculosis Drug Targets

Plug and Play Distributed Model Predictive Control Based on Distributed Invariance and Optimization

Extracellular matrix binding mixed micelles for drug delivery applications

Controlled release nanoparticle-embedded coatings reduce the tissue reaction to neuroprostheses

Characterization of New Potential Anticancer Drugs Designed To Overcome Glutathione Transferase Mediated Resistance

Co-Pathological Connected Primary Neurons in a Microfluidic Device for Alzheimer Studies

Polylactide-cyclosporin A nanoparticles for targeted immunosuppression

Reduction-Sensitive Tioguanine Prodrug Micelles

Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion

Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis