Concept

Rhodopsine

Publications associées (50)

Mechanism of ultrafast non-reactive deactivation of the retinal chromophore in non-polar solvents

The photoisomerization of the all-trans protonated Schiff base of retinal (SBR+) in solution is highly inefficient. The present theoretical and experimental investigation aims at disclosing the mechanisms of ultrafast, non-reactive relaxation of SBR+ that ...

Royal Soc Chemistry2017

Pull-Out Behavior of CFRP Single-Strap Ground Anchors

Thomas Keller, Anastasios Vassilopoulos, Haifeng Fan

Pull-out experiments were performed on four carbon fiber-reinforced polymer (CFRP) ground anchors simulating their applications in rock and soil. The CFRP tendons used in these anchors comprise a single-strap end on both ground and air sides. On the ground ...

American Society of Civil Engineers2017

Generalized QM/MM Force Matching Approach Applied to the 11-cis Protonated Schiff Base Chromophore of Rhodopsin

Ursula Röthlisberger, Ivano Tavernelli, Pablo Campomanes Ramos

We extended a previously developed force matching approach to systems with covalent QM/MM boundaries and describe its user-friendly implementation in the publicly available software package CPMD. We applied this approach to the challenging case of the reti ...

2014

Retinal pigment epithelium protein of 65 kDA gene-linked retinal degeneration is not modulated by chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C/chondroitin sulfate proteoglycan 5

Pascal Escher

Purpose: To analyze in vivo the function of chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C (gene symbol: Cspg5) during retinal degeneration in the Rpe65(-/-) mouse model of Leber congenital amaurosis. ...

Molecular Vision2013

Depletion-interaction effects on the tunneling conductivity of nanorod suspensions

Peter Ryser, Claudio Grimaldi, Biagio Nigro

We study by simulation and theory how the addition of insulating spherical particles affects the conductivity of fluids of conducting rods, modeled by spherocylinders. The electrical connections are implemented as tunneling processes, leading to a more det ...

American Physical Society2013

Retinal and post-retinal contributions to the quantum efficiency of the human eye revealed by electrical neuroimaging

Enrico Pomarico, Nicolas Gisin

The retina is one of the best known quantum detectors with rods able to reliably respond to single photons. However, estimates on the number of photons eliciting conscious perception, based on signal detection theory, are systematically above these values ...

Frontiers Research Foundation2013

How are non-retinotopic motion signals integrated? -A high-density EEG study

Michael Herzog, Gijs Plomp, Yvonne Evelina Thunell

Objects moving in the visual scene cause retinal displacements that are not the result of motor commands and thus cannot be accounted for by efference copies. Yet, we easily keep track of moving objects even without following them with our gaze. Here, we i ...

2013

Early apoptosis of rod photoreceptors in Rpe65(-/-) mice is associated with the upregulated expression of lysosomal-mediated autophagic genes

RPE65-related Leber's congenital amaurosis (LCA) is a rod-cone dystrophy whose clinical outcome is mainly attributed to the loss of rod photoreceptors followed by cone degeneration. Pathogenesis in Rpe65-/- mice is characterized by a slow and progressive d ...

2012

Convenient Preparation of Tri-tert-butylphosphonium Tetrafluoroborate

Nicolai Cramer, Tanguy Jean Daniel Saget

The versatile tri-tert-butylphosphonium tetrafluoroborate ligand is prepared in a convenient, simple, and high-yielding procedure without the isolation of sensitive intermediates. ...

2011

Exploring G-Protein Coupled Receptor Activation with Multiscale Molecular Simulations

Stefano Vanni

This thesis is devoted to the study of the activation mechanism of G-protein coupled receptors (GPCRs), one of the largest and most diverse protein families in mammalian genomes, by means of different computer-based simulation techniques. Using force field ...

EPFL2011

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