Concept

Intrinsically photosensitive retinal ganglion cell

Publications associées (154)

Beyond Bouma's window: How to explain global aspects of crowding?

Michael Herzog, Gregory Francis, Adrien Christophe Doerig, Aaron Michael Clarke, Alban Bornet

In crowding, perception of an object deteriorates in the presence of nearby elements. Although crowding is a ubiquitous phenomenon, since elements are rarely seen in isolation, to date there exists no consensus on how to model it. Previous experiments show ...

2019

Object identity determines transsaccadic integration

Michael Herzog

Very little information is transferred across saccades. It is commonly thought that detailed vision starts mainly anew with each saccade. Here, we show that transsaccadic integration occurs even for very fine grained and unconscious information when object ...

2019

Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition

Chuanqiang Zhang

Background Optogenetic silencing techniques have expanded the causal understanding of the functions of diverse neuronal cell types in both the healthy and diseased brain. A widely used inhibitory optogenetic actuator is eNpHR3.0, an improved version of the ...

BMC2019

Spatially selective activation of the visual cortex via intraneural stimulation of the optic nerve

Silvestro Micera, Diego Ghezzi, Fiorenzo Artoni, Paola Vagni, Vivien Gaillet, Ariastity Mega Pratiwi, Dario Lipucci Di Paola

Retinal prostheses can restore a functional form of vision in patients affected by dystrophies of the outer retinal layer. Beyond clinical utility, prostheses for the stimulation of the optic nerve, the visual thalamus or the visual cortex could also serve ...

2019

A design methodology for charge-balanced stimulators based on anodic current variation monitoring

Alexandre Schmid, Reza Ranjandish

Charge balancing is a major safety concern in neural and functional electrical stimulation. This paper presents a novel and safe active charge balancing design methodology in which, after each cathodic and anodic stimulation pulse, the value of the remaini ...

2019

Mapping of real-time morphological changes in the neuronal cytoskeleton with label-free wide-field second-harmonic imaging: a case study of nocodazole

Sylvie Roke, Carlos Alberto Macias Romero, Pascal Jourdain, Marie Eve Pascale Didier, Claire Jacqueline Léa Teulon

We demonstrate the use of wide-field high-throughput second-harmonic (SH) microscopy for investigating cytoskeletal morphological changes on the single-cell level. The method allows for real-time, in vitro, label-free measurements of cytoskeletal changes t ...

SPIE-Intl Soc Optical Eng2019

Validation of a Foldable and Photovoltaic Wide-Field Epiretinal Prosthesis

Diego Ghezzi

Inspired by intra ocular lenses, we designed a foldable and wide-field epiretinal prosthesis capable of achieving a wireless photovoltaic stimulation of retinal ganglion cells with a remarkable increase in its retinal coverage and in the number of stimulat ...

2018

Upper stimulation threshold for retinal ganglion cell activation

Diego Ghezzi

Objective. The existence of an upper threshold in electrically stimulated retinal ganglion cells (RGCs) is of interest because of its relevance to the development of visual prosthetic devices, which are designed to restore partial sight to blind patients. ...

2018

Exploring the use of native spider silk as an optical fibre for chemical sensing

Luc Thévenaz, Isabelle Dicaire, Kenny Hey Tow, Desmond Chow Ming Chia

A spider uses up to seven different types of silk, all having specific functions, as building material, weapon and sensory organ to detect the presence of preys on its web. Recently, scientists have put under the limelight the extraordinary properties of t ...

2018

Semi-automatic 3D morphological reconstruction of neurons with densely branching morphology: Application to retinal All amacrine cells imaged with multi -photon excitation microscopy

Bas-Jan Zandt

Background: Accurate reconstruction of the morphology of single neurons is important for morphometric studies and for developing compartmental models. However, manual morphological reconstruction can be extremely time-consuming and error-prone and algorith ...

Elsevier2017

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