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A plastid-like organelle, the apicoplast, is essential to the majority of medically and veterinary important apicomplexan protozoa including Toxoplasma gondii and Plasmodium. The apicoplast contains multiple copies of a 35 kb genome, the replication of whi ...
The variability of the T-RFLP analysis applied to complex microbial communities was assessed statistically. Recent technological improvements were implemented in the successive steps of the procedure, resulting in a standardized procedure which provided a ...
Widely used in industrial activities, chloroethenes have become common groundwater contaminants. Dehalorespiration is an anaerobic bacterial respiration coupling their sequential degradation to energy production. The interactions between the dehalorespirin ...
DNA photolyase is a highly efficient light-driven enzyme that repairs the UV-induced cyclobutane pyrimidine dimer in damaged DNA. Herein, we investigate the repair reaction of the thymine dimer by means of hybrid quantum mechanical/molecular mechanical QM/ ...
Homing endonucleases, also known as meganucleases, are sequence-specific enzymes with large DNA recognition sites. These enzymes can be used to induce efficient homologous gene targeting in cells and plants, opening perspectives for genome engineering with ...
The visualization of complex cellular processes involving multiple proteins requires the use of spectroscopically distinguishable fluorescent reporters. We have previously introduced the SNAP-tag as a general tool for the specific labeling of SNAP-tag fusi ...
The tunneling-percolation mechanism of conduction in disordered conductor-insulator composites is studied for a realistic continuum model where conducting and impenetrable spherical particles are dispersed in a three-dimensional continuum insulating materi ...
Proteolysis with proteases preloaded within nanopores of porous material is a very fast process, where proteins can be digested in minutes compared to the conventional bulk enzyme reactions taking place over hours. To model this surprising phenomenon, a mo ...
ABSTRACT: Human APOBEC3 proteins are editing enzymes that can interfere with the replication of exogenous retroviruses such as human immunodeficiency virus (HIV), hepadnaviruses such as hepatitis B virus (HBV), and with the retrotransposition of endogenous ...
In this paper, the steady-state performance of the distributed least mean-squares (dLMS) algorithm within an incremental network is evaluated without the restriction of Gaussian distributed inputs. Computer simulations are presented to verify the derived p ...